Fig. 2. Sequence alignment of E.coli FadR (FADR_ECOLI) and putative FadRs from Haemophilus influenzae (FADR_HAEIN) and Vibrio cholerae (FADR_VBCHO), together with a representative group of signature sequences from the GntR family, indicated by their standard SwissProt accession codes. FadR sequence numbering is used, and the secondary structure elements are indicated by bars and arrows. Conserved residues are indicated by black boxes. Residues touching the acyl-CoA ligand or the DNA helix are indicated by black circles.