Table 1. Ang II-induced increases in blood pressure variability (BPV).

(A-B) Summary data of calculated two-day average real variability of MAP, SBP, DBP, and PP during the active period (A) and the inactive period (B). Baseline corresponds to (~5-day saline infusion) and ‘*’ denotes within group comparisons (p<0.05 vs Baseline) and ‘#’ denotes p<0.05 between groups comparisons. Two-way ANOVA repeated measures followed by Dunnett’s comparison test; n = 13 control mice, n = 8 BPV mice.

	ARV mmHg ±SEM (Active)
	MAP								SBP								DBP								PP
Days	Control				BPV				Control				BPV				Control				BPV				Control				BPV
Baseline	12.44	±	1.37		10.94	±	0.55		14.15	±	1.49		13.13	±	0.66		11.53	±	1.44		9.04	±	0.54		4.67	±	0.4		5.47	±	0.46
1–2	12.91	±	1.29		10.99	±	0.35		14.86	±	1.28		14.56	±	0.44		11.7	±	1.48		9.29	±	0.41		5.12	±	0.4		7.67	±	0.69
3–4	12.44	±	0.66		12.51	±	0.43		14.4	±	0.67		16.4	±	0.66	*	11.12	±	0.83		10.35	±	0.45		5.03	±	0.33		8.12	±	0.71	*#
5–6	11.78	±	0.52		12.8	±	0.39		13.64	±	0.61		16.44	±	0.53	*#	10.71	±	0.73		10.54	±	0.45		4.89	±	0.32		7.99	±	0.69	*#
7–8	12.35	±	0.61		12.85	±	0.41	*	14.02	±	0.67		16.73	±	0.43	*#	11.37	±	0.81		10.61	±	0.55	*	5.22	±	0.42		8.34	±	0.74	*#
9–10	12.34	±	0.69		12.84	±	0.4		13.88	±	0.75		16.37	±	0.72		11.32	±	0.79		10.82	±	0.24		4.95	±	0.39		7.86	±	0.65	*#
11–12	13	±	0.76		12.94	±	0.76	*	14.59	±	0.88		16.87	±	0.7	*	11.93	±	0.93		10.59	±	0.81		5.05	±	0.34		8.25	±	0.78	#
13–14	12.26	±	0.84		12.9	±	0.42	*	13.94	±	0.84		16.8	±	0.52	*	11.17	±	0.95		10.4	±	0.68	*	5.07	±	0.39		8.45	±	0.83	#
15–16	13.27	±	0.59		13.91	±	1.02		15.11	±	0.81		17.5	±	0.87	*	11.72	±	0.82		11.59	±	1.14		5.24	±	0.38		8.25	±	0.73	*
17–18	13.12	±	0.77		14.06	±	0.92		15.16	±	1.03		17.12	±	0.77	*	11.99	±	0.85		11.95	±	1.19		5.48	±	0.58		7.6	±	0.77
19–20	12.62	±	0.45		12.75	±	0.92		14.75	±	0.52		16.57	±	0.94		11.09	±	0.7		10.48	±	1.23		6.32	±	0.6		8.44	±	1.15
	ARV mmHg ±SEM (Inactive)
	MAP								SBP								DBP								PP
Days	Control				BPV				Control				BPV				Control				BPV				Control				BPV
Baseline	12.09	±	1.38		11.29	±	0.54		13.53	±	1.5		13.28	±	0.7		11.27	±	1.4		9.48	±	0.45		4.74	±	0.47		5.04	±	0.45
1–2	12.15	±	1.04		11.4	±	0.69		14.08	±	1.03		14.69	±	0.77		10.95	±	1.15		9.76	±	0.68		4.92	±	0.24		7.09	±	0.55
3–4	12.23	±	0.79		13.38	±	0.33	*	14.02	±	0.76		17.27	±	0.48	*#	11.19	±	1.02		11.29	±	0.47	*	4.76	±	0.32		7.9	±	0.55	*#
5–6	12.16	±	0.43		13.63	±	0.78	*	14.2	±	0.52		17.57	±	0.78	*#	10.68	±	0.53		11.34	±	0.86		4.95	±	0.3		8.23	±	0.69	*#
7–8	11.95	±	0.49		13.73	±	0.5	*	13.64	±	0.54		17.44	±	0.53	*#	10.88	±	0.59		11.61	±	0.67	*	4.9	±	0.32		8.45	±	0.89
9–10	12.9	±	1.28		14.77	±	0.66	*	14.71	±	1.49		18.52	±	0.72	*	11.92	±	1.15		12.59	±	0.64	*	5.33	±	0.31		8.16	±	0.61	*#
11–12	12.49	±	0.79		14.53	±	0.57	*	14.09	±	0.82		18.65	±	0.62	*#	11.5	±	1.07		12.09	±	0.74	*	5.24	±	0.31		8.5	±	0.88
13–14	13.03	±	0.75		13.96	±	0.74	*	14.85	±	0.82		17.65	±	0.53	*	11.94	±	0.99		11.56	±	0.92		5.1	±	0.38		8.16	±	0.74	*#
15–16	13.35	±	0.79		15.04	±	0.87	*	14.87	±	0.93		18.85	±	0.87	*	12.21	±	0.98		12.66	±	1.07		4.97	±	0.36		8.54	±	1.06	*
17–18	12.99	±	0.7		15.61	±	1.36		14.19	±	0.82		19.39	±	1.09	*#	11.47	±	0.83		13.18	±	1.67		5.02	±	0.4		8.46	±	1.03
19–20	12.89	±	0.57		14.72	±	1	*	15.13	±	0.74		18.96	±	0.96	*	11.36	±	0.65		12.19	±	1.25		6.21	±	0.4		9.28	±	1.33

ARV=average real variability, BPV=blood pressure variability, DBP=diastolic blood pressure, MAP=mean arterial pressure, PP=pulse pressure, SBP=systolic blood pressure.