Table 2.

Levels of cortisol-related hormones.

	KC	LVC	P value
Cortisol (pg/mL)	1660.95 [1175.01–2408.81]	945.60 [550.36–1699.32]	0.023
P5 (pg/mL)	168.97 [5.00–227.31]	161.46 [5.00–215.02]	0.856
P4 (pg/mL)	5.00 [5.00–5.00]	5.00 [5.00–5.00]	0.587
17-OHP5 (pg/mL)	173.35 [96.14–328.98]	126.91 [76.94–187.46]	0.247
17-OHP (pg/mL)	52.40 [32.35–75.40]	51.37 [38.69–96.49]	0.546
11-DF (pg/mL)	13.39 [7.03–34.52]	10.03 [5.50–16.33]	0.137
21-DF (pg/mL)	23.57 [2.00–28.96]	22.34 [2.00–33.46]	0.979

Continuous data were expressed as median [IQR] for non-normally distributed data (Mann–Whitney U test). The primary outcome was tear cortisol; comparisons of the six other cortisol-related hormones used the Mann–Whitney U test with Bonferroni correction. LVC = laser vision correction; KC = keratoconus; P5 = pregnenolone; P4 = progesterone; 17-OHP5 = 17α-Hydroxypregnenolone; 17-OHP = 17α-Hydroxyprogesterone; 11-DF = 11-Deoxycortisol; 21-DF = 21-Deoxycortisol.