Table 1.
Summary of the clinical characteristics of the participants including demographics and concomitant medical conditions.
| Population Demographics | No. Of participants (%) | p-value | ||
|---|---|---|---|---|
| Overall (n = 64) |
Survived (n = 53) |
Deceased (n = 11) |
||
| Age (years) | 66.4 ± 15.6 | 65.6 ± 14.9 | 70.6 ± 18.8 | 0.33 |
| Age at diagnosis (years) | 61.0 ± 16.0 | 59.5 ± 15.1 | 69.0 ± 19.2 | 0.09 |
| Smoker | 12 (18.8) | 10 (18.9) | 2 (18.2) | 1.0 |
| Male Gender | 39 (60.9) | 30 (56.6) | 9 (81.8) | 0.22 |
| Ethnicity | 0.08 | |||
| Chinese | 45 (70.3) | 37 (69.8) | 8 (72.7) | |
| Malay | 9 (14.1) | 8 (15.1) | 1 (9.1) | |
| Indian | 3 (4.7) | 1 (1.9) | 2 (18.2) | |
| Others | 7 (10.9) | 7 (13.2) | 0 (0.0) | |
| Body Mass Index (kg/m2) | 24.4 ± 6.0 | 24.6 ± 6.0 | 23.4 ± 5.8 | 0.58 |
| Concomitant Medical Conditions | ||||
| Cardiovascular Risk Factors | ||||
| Hypertension | 29 (45.3) | 22 (41.5) | 7 (63.6) | 0.31 |
| Hyperlipidaemia | 25 (39.1) | 18 (34.0) | 7 (63.6) | 0.14 |
| Diabetes Mellitus | 11 (17.2) | 6 (11.3) | 5 (45.5) | 0.02 |
| Peripheral Vascular Disease | 1 (1.6, n = 63) | 0 (0.0, n = 52) | 1 (9.1) | 0.39 |
| Cardiac | ||||
| Ischaemic Heart Disease | 7 (10.9) | 2 (3.8) | 5 (45.5) | < 0.001 |
| Atrial Fibrillation | 2 (3.1) | 1 (1.9) | 1 (9.1) | 0.77 |
| Congestive Cardiac Failure | 1 (1.6) | 0 (0.0) | 1 (9.1) | 0.38 |
| Others | ||||
| Stroke/Transient Ischaemic Attack | 11 (17.2) | 10 (18.9) | 1 (9.1) | 0.73 |
| Hemiplegic | 1 (1.6) | 1 (1.9) | 0 (0.0) | 1.0 |
| Chronic Kidney Disease | 7 (10.9) | 1 (1.9) | 6 (54.5) | < 0.001 |
| Chronic Obstructive Pulmonary Disease | 2 (3.1) | 2 (3.8) | 0 (0.0) | 1.0 |
| Malignancy | 4 (6.2) | 3 (5.7) | 1 (9.1) | 1.0 |
| Dementia | 1 (1.6) | 1 (1.9) | 0 (0.0) | 1.0 |
| Connective Tissue Disease | 2 (3.1) | 1 (1.9) | 1 (9.1) | 0.77 |
| Outcomes | ||||
| Deaths | 11 (17.2) | - | - | - |
| Major Adverse Cardiovascular Events (MACE) | 10 (16.1, n = 62) | 3 (5.7) | 7 (77.8) | < 0.001 |
| Cardiovascular Death | 5 (7.8) | 0 (0.0) | 5 (45.5) | < 0.001 |
| Congestive Cardiac Failure | 4 (6.5, n = 62) | 1 (1.9) | 3 (33.3, n = 9) | 0.005 |
| Stroke | 3 (4.8, n = 62) | 1 (1.9) | 2 (22.2, n = 9) | 0.07 |
| Acute Myocardial Infarction | 4 (6.5, n = 62) | 1 (1.9) | 3 (33.3, n = 9) | 0.005 |