Table 3.
Relationship between miR-21 and Adropin levels in the study groups (n = 128).
| miR-21 | Adropin | |||
|---|---|---|---|---|
| r | p | r | p | |
| Age (years) | 0.171 | 0.064 | −0.146 | 0.114 |
| Body mass index (kg/m 2 ) | 0.230 | 0.012 | −0.399 | < 0.001 |
| Fasting Blood Glucose (mg/dL) | −0.088 | 0.340 | −0.165 | 0.074 |
| HbA1c (%) | −0.143 | 0.121 | −0.182 | 0.047 |
| Total cholesterol (mg/dL) | 0.029 | 0.754 | −0.130 | 0.159 |
| HDL (mg/dL) | −0.142 | 0.124 | 0.106 | 0.251 |
| LDL (mg/dL) | −0.038 | 0.680 | −0.025 | 0.784 |
| Triglyceride (mg/dL) * | 0.091 | 0.327 | −0.181 | 0.049 |
| Creatinine (mg/dL) | −0.033 | 0.721 | −0.020 | 0.832 |
| Creatinine clearance (mL/min) | −0.265 | 0.004 | 0.171 | 0.064 |
| Albumin: creatinine ratio* | 0.126 | 0.242 | −0.145 | 0.176 |
| CRP (mg/L) * | −0.010 | 0.910 | −0.085 | 0.355 |
| Adropin (ng/L) * | −0.667 | < 0.001 | ||
| CIMT (mm) | 0.438 | < 0.001 | −0.585 | < 0.001 |
Abbreviations: CIMT = Carotid Intima-Media Thickness. All correlations were calculated across all participants, including healthy controls and patient groups.
Statistical tests: Correlations were assessed using Pearson’s correlation coefficient for normally distributed data or Spearman’s rank correlation for non-normal data and are indicated by an asterisk (*). A two-tailed p < 0.05 was considered significant.