Table II. Comparison of efficiency of production of the immunodominant epitope SIINFEKL and N-extended variants by 26S proteasomes and immunoproteasomes.
| Peptide | Proteasomes | Immunoproteasomes |
|---|---|---|
| (pmol produced/100 pmol ovalbumin digested) | ||
| S | 2.0 ± 0.5 | 1.8 ± 0.5 |
| 1+S | 1.4 ± 0 | 4.1 ± 0.7 |
| 2+S | 0.4 ± 0.1 | 0.3 ± 0.1 |
| 3+S | 0.6 ± 0.1 | 0.7 ± 0.2 |
| 4+S | 0.6 ± 0 | 1.5 ± 0.2 |
| 6+S | 0.4 ± 0.2 | 0.8 ± 0.2 |
| 7+S | 1.0 ± 0.1 | 1.6 ± 0.3 |
| Total S-containing peptides | 6.4 ± 0.6 | 10.8 ± 1.8 |
| Total N-extended versions | 4.4 ± 0.3 | 9.0 ± 1.4 |
| % extended | 69% | 83% |
Values are mean ± SE.