Table III. Comparison of efficiency of production of the immunodominant epitope SIINFEKL and N-extended variants by 20S proteasomes and immunoproteasomes.
| Peptide | Proteasomes | Immunoproteasomes |
|---|---|---|
| (pmol produced/100 pmol ovalbumin digested) | ||
| S | 2.0 ± 0.2 | 1.2 ± 0.3 |
| 1+S | 2.8 ± 0.6 | 5.8 ± 1.5 |
| 2+S | 0.3 ± 0.1 | 0.1 ± 0 |
| 3+S | 0.6 ± 0 | 0.5 ± 0 |
| 4+S | 1.1 ± 0.2 | 1.3 ± 0.2 |
| 6+S | 0.3 ± 0 | 0.5 ± 0 |
| 7+S | 0.9 ± 0 | 1.2 ± 0.1 |
| Total S-containing peptides | 8.0 ± 0 | 10.6 ± 0.9 |
| Total N-extended versions | 6.0 ± 0.2 | 9.4 ± 1.2 |
| % extended | 75% | 89% |
Values are mean ± SE.