Fig. 6. Survival curve for wild-type and MEK5DD transgenic mice. F1 hemizygous transgenic mice were generated by backcrossing the transgenic founder mouse with C57B6 mice. The open circles represent the percentage survival of wild-type (WT) F1 mice (n = 24); the closed circles represent percentage survival of transgenic (TG) F1 mice (n = 24).