Table 2.
Objective tumor response
| Variable, N (%) | Total (N = 338) |
Low-eGFR groupa (N = 176) |
High-eGFR groupb (N = 162) |
P-value |
| Objective tumor response | ||||
| CR | 3 (0.9) | 3 (1.7) | 0 | |
| PR | 75 (22.2) | 39 (22.2) | 36 (22.2) | |
| SD | 194 (57.4) | 107 (60.8) | 87 (53.7) | |
| PD | 58 (17.2) | 21 (11.9) | 37 (22.8) | |
| NE | 8 (2.4) | 6 (3.4) | 2 (1.2) | |
| Response rate | 78 (23.1) | 42 (23.9) | 36 (22.2) | 0.7205 |
| Disease control rate | 272 (80.5) | 149 (84.7) | 123 (75.9) | 0.043 |
CR: complete response
eGFR: estimated glomerular filtration rate
NE: not evaluable
PD: progressive disease
PR: partial response
SD: stable disease
a Patients with an eGFR < 80 mL/min/1.73 m2
b Patients with an eGFR ≥ 80 mL/min/1.73 m2