Table 5.
Statistical comparison of the obtained results by applying the developed methods and the official method for the determination of PHE and DOX in their pharmaceutical preparation. a average of 6 experiments. b figures between parentheses represent the corresponding tabulated values of t and f at P = 0.05.
| Value | PHE | DOX | ||||
|---|---|---|---|---|---|---|
| HPLC method | HPTLC method | Official method14 | HPLC method | HPTLC method | Official method14 | |
| Mean (%)a | 99.68 | 99.15 | 101.29 | 99.41 | 99.64 | 100.35 |
| SD | 0.576 | 0.468 | 1.595 | 0.659 | 1.213 | 1.135 |
| n | 3 | 3 | 3 | 3 | 3 | 3 |
| Variance | 0.331 | 0.219 | - | 0.433 | 1.47 | - |
| Student’s t-test (2.78) b | 1.64 | 2.23 | - | 1.24 | 0.74 | - |
| F value (19.05) b | 7.68 | 11.60 | - | 2.97 | 1.14 | - |