Table 3.

Protective thresholds by serotype and age at onset

Serotype	Age at onset	0.75 protective threshold (mcg/mL)	0.8 protective threshold (mcg/mL)	0.9 protective threshold (mcg/mL)	Zero risk protective threshold (mcg/mL)
IA	EOD	1.61 (0.53–4.92)	2.49 (0.81–7.67)	8.49 (1.76–41.01)	9.08 (8.51–11.78)
IA	LOD	0.01 (0–0.08)	0.02 (0–0.11)	0.07 (0.02–0.29)	1.25 (0.94–30.82)
IB	EOD	0.48 (0.01–16.92)	1.13 (0.02–70.83)	16.34 (0.04–6052.37)	6.54 (4.85–168.06)
IB	LOD	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	0.10 (0.09–0.36)
II	EOD	12.91 (12.24–43.37)*	12.91 (12.24–43.37)*	12.91 (12.24–43.37)*	12.91 (12.24–43.37)
II	LOD	0.59 (0.53–6.02)*	0.59 (0.53–6.02)*	0.59 (0.53–6.02)*	0.59 (0.53–6.02)
III	EOD	0.27 (0.05–1.41)	0.52 (0.07–3.57)	4.04 (0.26–64.04)	1.53 (1.31–22.17)
III	LOD	0.03 (0.01–0.06)	0.04 (0.02–0.08)	0.09 (0.05–0.17)	0.92 (0.7–21.8)
IV	EOD	2.85 (2.36–39.97)*	2.85 (2.36–39.97)*	2.85 (2.36–39.97)*	2.85 (2.36–39.97)
IV	LOD	0.08 (0–1.60)	0.14 (0.01–2.41)	0.85 (0.01–72.79)	0.87 (0.66–21.28)
V	EOD	5.25 (4.81–35.22)*	5.25 (4.81–35.22)*	55.25 (4.81–35.22)*	5.25 (4.81–35.22)
V	LOD	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	Sample size <5 above lower limit of quantification so curve not generated and zero risk protective threshold used	1.76 (1.27–50.6)

*Step function so zero risk protective threshold used.