Table 2.
Changes of Ocular and ONH Characteristics over Time, Generalized Linear Mixed-Effect Model Analysis
| Characteristics | Baseline | Last ATOM2 Visit | ATLAS Recall | Estimate | Standard Error | P Value |
|---|---|---|---|---|---|---|
| Ocular Characteristics | ||||||
| Spherical equivalent refraction, D | –4.54 ± 1.64 | –6.35 ± 2.02 | –6.88 ± 2.40 | –0.1413 | 0.006 | <0.0001 |
| Axial length, mm | 25.08 ± 0.89 | 25.93 ± 1.01 | 26.31 ± 1.17 | 0.076 | 0.002 | <0.0001 |
| ONH characteristics | ||||||
| Ovality | 1.26 ± 0.13 | 1.30 ± 0.14 | 1.27 ± 0.14 | 0.000 | 0.000 | 0.260 |
| PPA ratio | 0.19 ± 0.11 | 0.24 ± 0.13 | 0.31 ± 0.15 | 0.007 | 0.000 | <0.0001 |
| Torsion angle, degree | 11.23 ± 11.42 | 11.39 ± 11.53 | 12.2 ± 12.57 | 0.071 | 0.035 | 0.043 |
| Disc–fovea distance ratio | 2.75 ± 0.33 | 2.75 ± 0.31 | 2.78 ± 0.35 | 0.002 | 0.001 | 0.016 |
| Position of CRVT | 1.62 ± 0.22 | 1.64 ± 0.36 | 2.23 ± 0.5 | 0.044 | 0.002 | <0.0001 |
| VDA ratio | 3.73 ± 0.82 | 3.68 ± 0.8 | 3.74 ± 0.85 | 0.001 | 0.001 | 0.180 |
| Angle kappa, degree | 66.20 ± 10.68 | 65.75 ± 10.4 | 65.81 ± 10.88 | –0.016 | 0.011 | 0.150 |
ATLAS = Atropine Treatment Long-Term Assessment Study; ATOM2 = Atropine for the Treatment of Myopia 2; CRVT = central retinal vascular trunk; D = diopters; ONH = optic nerve head; PPA = peripapillary atrophy; VDA = vertical arcade distance.
Bold values indicate statistical significant.