Table 3.
Univariate Generalized Linear Mixed-Effect Model Determination of Factors Associated with ONH Characteristics Changing over Time
| Univariate models | PPA Ratio |
Torsion |
Disc–Fovea Distance Ratio |
Position of CRVT |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estimate | Standard Error | P Value | Estimate | Standard Error | P Value | Estimate | Standard Error | P Value | Estimate | Standard Error | P Value | |
| Age | 0.008 | 0.000 | <0.0001 | 0.072 | 0.036 | 0.046 | 0.002 | 0.001 | 0.014 | 0.044 | 0.002 | <0.0001 |
| AL | 0.081 | 0.003 | <0.0001 | –0.005 | 0.324 | 0.990 | 0.019 | 0.008 | 0.012 | 0.261 | 0.016 | <0.0001 |
| SER | –9.915 | 0.436 | <0.0001 | 0.085 | 0.160 | 0.600 | –0.010 | 0.004 | 0.008 | –0.109 | 0.008 | <0.0001 |
| PPA ratio | –8.070 | 2.745 | 0.004 | 0.670 | 0.061 | <0.0001 | 2.160 | 0.123 | <0.0001 | |||
| Ovality | 0.493 | 0.032 | <0.0001 | –10.270 | 3.070 | 0.001 | 0.330 | 0.072 | <0.0001 | 0.798 | 0.138 | <0.0001 |
| Torsion | –0.002 | 0.000 | <0.0001 | –0.003 | 0.001 | <0.0001 | –0.001 | 0.002 | 0.480 | |||
| Disc–fovea distance ratio | 0.174 | 0.015 | <0.0001 | –6.220 | 1.380 | <0.0001 | 0.320 | 0.058 | <0.0001 | |||
| Position of CRVT | 0.125 | 0.006 | <0.0001 | –0.084 | 0.584 | 0.890 | 0.077 | 0.013 | <0.0001 | |||
| Atropine | 0.670 | 0.350 | 0.710 | 0.370 | ||||||||
| Atropine 0.1% | 0.007 | 0.026 | –2.630 | 2.090 | 0.002 | 0.066 | –0.087 | 0.066 | ||||
| Atropine 0.5% | –0.011 | 0.026 | –2.880 | 2.100 | –0.038 | 0.066 | –0.035 | 0.067 | ||||
| Retreatment, yes | 0.192 | 1.894 | 0.920 | 80.760 | 153.380 | 0.600 | –7.951 | 4.782 | 0.096 | –3.037 | 4.853 | 0.530 |
AL = axial length; CRVT = central retinal vascular trunk; ONH = optic nerve head; PPA = peripapillary atrophy; SER = spherical equivalent refraction.
Bold values indicate statistical significant.