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. 2001 Jul 2;20(13):3535–3543. doi: 10.1093/emboj/20.13.3535

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Fig. 2. (A) Western blot analysis of PARP-1 and p53 expression in nuclear (p53) or crude (PARP-1) extracts of MEFs of the indicated genotypes. p53 protein was induced after 5 Gy irradiation. (B) Southern blot of HindIII-digested DNA from parp-1+/+p53–/– and parp-1–/–p53–/– MEFs infected or not with H-ras V12 retrovirus, using the ras V12 probe. (C) Morphology of primary and transformed parp-1+/+p53+/+ and parp-1–/–p53 fibroblasts. (D) Anchorage-independent growth of transformed parp-1+/+p53–/– and parp-1–/–p53–/– fibroblasts.