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. 2025 Oct 10;62:101968. doi: 10.1016/j.gore.2025.101968

Table 1.

Reggio Emilia Cancer Registry. Vulvar and vaginal cancer, years 1996–2021. Number of cases by age, period of diagnosis, morphology, method of diagnosis, and nationality.

All
Vulva
Vagina
n % n % n %
Overall 328 264 80.5 64 19.5
Age at diagnosis
<50 13 4.0 6 2.3 7 10.9
50–69 84 25.6 66 25.0 18 28.1
70+ 231 70.4 192 72.7 39 61.0
mean sd mean sd mean sd
74.9 12.8 76.1 11.9 70.2 15.1
Period of diagnosis
1996–2000 74 22.6 54 20.5 20 31.2
2001–2005 59 18.0 51 19.3 8 12.5
2006–2010 62 18.9 50 18.9 12 18.8
2011–2015 63 19.2 53 20.1 10 15.6
2016–2021 70 21.3* 56 21.2 14 21.9
Morphology
Squamous cell carcinomas 243 74.1 206 78.0 37 57.8
Basal cell carcinomas 19 5.8 19 7.2 0 0.0
Adenocarcinomas 11 3.4 1 0.4 10 15.6
Ductal and lobular carcinomas 13 4.0 13 4.9 0 0.0
Nevi and melanomas 18 5.5 14 5.3 4 6.3
Other 24 7.3 11 4.2 13 20.3
Method of diagnosis
Clinical/instrumental 8 2.4 5 1.9 3 4.7
Histological 320 97.6 259 98.1 61 95.3
Population
Italians 319 97.3 260 98.5 59 92.2
Non-Italians 9 2.7 4 1.5 5 7.8