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Frequency of pathogenic genomic alterations in the tumor at diagnosis
| Genomic Alteration | No. Present (%) | No. Absent (%) | No. Not tested (%) |
|---|---|---|---|
| MGMT promoter methylation | 51 (29.1) | 123 (70.3) | 1 (0.6) |
| TERT variant | 55 (31.4) | 24 (13.7) | 96 (54.9) |
| EGFR amplification | 38 (21.7) | 52 (29.7) | 85 (48.6) |
| TP53 variant | 33 (18.9) | 45 (25.7) | 97 (55.4) |
| PTEN variant | 22 (12.6) | 57 (32.6) | 96 (54.8) |
| EGFR variant | 20 (11.4) | 70 (40.0) | 85 (48.6) |
| PIK3CA variant | 10 (5.7) | 74 (42.3) | 91 (52.0) |
