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. 2025 Sep 19;104(9):4465–4476. doi: 10.1007/s00277-025-06604-7

Table 2.

Genotyping of α-thalassemia in Putian

	Genotype	Number of cases(n)	Constituent ratio (%)
Common α-thalassemia	--^SEA/αα	1020	71.93
	-α^3.7/αα	199	14.03
	--^SEA/-α^3.7	37	2.61
	-α^4.2/αα	32	2.26
	αα^CS/αα	31	2.19
	αα^WS/αα	23	1.62
	αα^QS/αα	19	1.34
	--^SEA/-α^4.2	12	0.85
	-α^3.7/-α^3.7	8	0.56
	--^SEA/αα^QS	3	0.21
	--^SEA/αα^WS	2	0.14
	--^SEA/--^SEA	2	0.14
	-α^3.7/αα^CS	2	0.14
	-α^3.7/-α^4.2	1	0.07
	-α^3.7/αα^QS	1	0.07
	αα^QS/αα^QS	1	0.07
	-α^4.2/-α^4.2	1	0.07
	-α^4.2/αα^QS	1	0.07
	--^SEA/αα^CS	1	0.07
	αα^WS/αα^WS	1	0.07
Rare α-thalassemia	ααα^anti4.2	6	0.42
	--^THAI/αα	4	0.28
	HBA1:c.223G > C	3	0.21
	Hkαα/--^SEA	1	0.07
	-α^3.7/--^THAI	1	0.07
	-α^4.2/--^THAI	1	0.07
	ααα^anti3.7	1	0.07
	HBA1:c.300 + 55G > T	1	0.07
	HBA1 :c.364G > A	1	0.07
	HBA2:c.49 A > T	1	0.07
	HBA2 :c.34 A > C	1	0.07
Total		1418	100.00