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. 2025 Oct 24;15:37213. doi: 10.1038/s41598-025-21039-w

Table 2.

Performance of the four autoantibodies in differentiating SLE patients from SS patients when specificity is set to 95%.

Antibody Cut Off Sensitivity Specificity
Anti-dsDNA 100 52.78% 90.80%
Anti-Nucl 20 44.91% 90.80%
Anti-Rib P 20 17.59% 97.70%
Anti-C1q 20 15.28% 98.85%
Specificity of assays is defined at 95%
Anti-dsDNA 188 41.20% 95.40%
Anti-Nucl 58 32.87% 95.40%
Anti-Rib P 20 17.59% 97.70%
Anti-C1q 20 15.28% 98.85%

Anti-dsDNA: anti-double-stranded DNA antibodies; Anti-Nucl: anti-nucleosome antibodies; Anti-Rib P: anti-ribosomal P antibodies; Anti-C1q: anti-c1q antibodies