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. 2025 Oct 24;15:37213. doi: 10.1038/s41598-025-21039-w

Table 3.

Biological characteristics of SS patients with or without SLE-associated autoantibodies.

Biological characteristics All SS patients
(n = 87)
SS patients with SLE-associated autoantibodies
(n = 13)
SS patients without SLE-associated autoantibodies
(n = 74)
P value
ANA positivity 0.340
≤ 1:100 ANA (n, %) 11,(12.64%) 1,(7.69%) 10,(13.51%)
1:320 ANA (n, %) 12,(13.79%) 1,(7.69%) 11,(14.86%)
1:1000 ANA (n, %) 45,(51.72%) 5,(38.46%) 40,(54.05%)
≥ 1:3200 ANA (n, %) 19,(21.84%) 6,(46.15%) 13,(17.58%)
Anti-ENA Abs positivity
anti-SSA (n, %) 64,(73.56%) 11,(84.62%) 53,(71.62%) 0.330
anti-SSB (n, %) 29,(33.33%) 4,(30.77%) 25,(33.78%) 0.833
anti-nRNP/Sm (n, %) 7,(8.05%) 4,(30.77%) 3,(4.05%) 0.001***
anti-Sm (n, %) 1,(1.15%) 0,(0%) 1,(1.35%) 0.675
anti- Scl-70 (n, %) 0,(0%) 0,(0%) 0,(0%) 1.000
anti- Ro52 (n, %) 67,(77.01%) 11,(84.62%) 56,(75.68%) 0.482
anti- Jo-1 (n, %) 3,(3.45%) 1,(7.69%) 2,(2.70%) 0.366
anti-CENP-B (n, %) 7,(8.05%) 0,(0%) 7,(9.46%) 0.250

Abs: antibodies; ENA: Extractable nuclear antigen; *P<0.05; **P<0.01; ***P<0.001.