Table I.

MR estimates for AD and AA

Analysis type	Exposure	Outcome	Method	OR (95% CI)	P value
Univariable	AD	AA	MR-Egger	1.45 (1.12-1.88)	.01
—	—	—	Weighted median	1.59 (1.38-1.83)	<.001
—	—	—	IVW	1.64 (1.49-1.81)	<.001
—	—	—	Simple mode	1.53 (1.17-2.00)	.005
—	—	—	Weighted mode	1.55 (1.22-1.96)	.002
Reverse MR	AA	AD	MR-Egger	1.17 (0.99-1.37)	.08
—	—	—	Weighted median	1.25 (1.19-1.33)	<.001
—	—	—	IVW	1.23 (1.18-1.28)	<.001
—	—	—	Simple mode	1.28 (1.16-1.41)	<.001
—	—	—	Weighted mode	1.27 (1.15-1.40)	<.001
Multivariable	AD	AA	Multivariable IVW	1.38 (1.27-1.49)	<.001
—	HDL	—	—	0.99 (0.90-1.09)	.83
—	LDL	—	—	1.04 (0.94-1.16)	.43
—	Triglycerides	—	—	1.06 (0.95-1.17)	.29
—	Basophils	—	—	0.93 (0.81-1.08)	.37
—	Lymphocytes	—	—	0.90 (0.82-1.00)	.04
—	Eosinophils	—	—	1.40 (1.26-1.54)	<.001