Table 2.
Serial mediation outcomes linking brain, alexithymia, and e-cigarette use.
| Task Performance W1b (M1) | Difficulty Describing Feelings W1b (M2) | E-cigarette Use W2 (Y) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| lPFC (activation) | Coefficient | (95 % CI) | SE | z Value | Coefficient | (95 % CI) | SE | z Value | Coefficient | (95 % CI) | SE | z Value |
| Intercept | 3.14 | (−0.02, 1.04) | 0.27 | 1.86 | 1.18 | (−10.36, 21.20) | 7.84 | 0.70 | −2.46 | (−177.15, 18.52) | 51.53 | −1.38 |
| Age | 0.01 | (−0.03, 0.04) | 0.02 | 0.10 | 0.11 | (−0.25, 1.70) | 0.50 | 1.49 | 0.09 | (−2.76, 11.32) | 3.54 | 1.09 |
| Sexa | −0.09 | (−0.08, 0.02) | 0.03 | −1.11 | −1.17* | (−3.10, 0.04) | 0.77 | −1.99 | 0.12 | (−2.58, 19.36) | 5.54 | 1.26 |
| Ethnicityb | −0.03 | (−0.11, 0.08) | 0.05 | −0.33 | 0.11 | (−0.62, 3.69) | 1.07 | 1.33 | −0.08 | (−20.63, 4.08) | 6.46 | −0.99 |
| Lifetime E-Cig. Use (W1a) | 0.01 | (−0.06, 0.07) | 0.03 | 0.08 | −0.07 | (−2.32, 0.75) | 0.78 | −0.89 | 0.25* | (3.74, 28.45) | 6.47 | 2.34 |
| R lPFC (W1b) | 0.27** | (0.05, 0.35) | 0.07 | 2.77 | −0.16* | (−7.09, −0.11) | 1.73 | −2.00 | 0.002 | (−20.51, 18.62) | 9.84 | 0.02 |
| Task Performance (W1b) | - | - | - | - | −0.13 | (−8.70, 1.23) | 2.50 | −1.49 | 0.02 | (−21.79, 25.69) | 11.67 | 0.34 |
| Difficulty Describing Feelings (W1b) | - | - | - | - | - | - | - | - | 0.20* | (0.22, 2.54) | 0.60 | 2.05 |
| R2= 0.08 | R2= 0.11 | R2= 0.12 | ||||||||||
| STG (deactivation) | Task Performance W1b (M1) | Difficulty Describing Feelings W1b (M2) | E-cigarette Use W2 (Y) | |||||||||
| Intercept | 2.86 | (−0.15, 1.02) | 0.29 | 1.62 | 1.35 | (−7.83, 19.88) | 7.51 | 0.83 | −2.47 | (−171.30, 25.25) | 50.82 | −1.41 |
| Age | 0.03 | (−0.03, 0.05) | 0.02 | 0.40 | 0.10 | (−0.22, 1.68) | 0.50 | 1.34 | 0.09 | (−3.28, 10.45) | 3.42 | 1.08 |
| Sexa | −0.10 | (−0.09, 0.03) | 0.03 | −1.14 | −0.16† | (−2.99, 0.10) | 0.78 | −1.89 | 0.12 | (−2.17, 20.01) | 5.71 | 1.17 |
| Ethnicityb | −0.03 | (−0.09, 0.08) | 0.05 | −0.26 | 0.11 | (−0.84, 3.61) | 1.14 | 1.23 | −0.08 | (−21.97, 3.62) | 6.75 | −1.00 |
| Lifetime E-Cig. Use (W1a) | −0.03 | (−0.07, 0.05) | 0.03 | −0.30 | −0.05 | (−2.08, 1.08) | 0.79 | −0.64 | 0.25* | (4.14, 28.60) | 6.42 | 2.34 |
| L STG (W1b) | −0.26** | (−0.32, −0.05) | 0.06 | −2.84 | 0.20* | (0.73, 7.85) | 1.78 | 2.17 | −0.06 | (−24.01, 8.62) | 8.15 | −0.89 |
| Task Performance (W1b) | - | - | - | - | −0.12 | (−8.55, 1.03) | 2.39 | −1.47 | 0.01 | (−22.61, 25.82) | 11.87 | 0.14 |
| Difficulty Describing Feelings (W1b) | - | - | - | - | - | - | - | - | 0.21* | (0.28, 2.71) | 0.63 | 2.07 |
| R2= 0.07 | R2= 0.12 | R2= 0.12 | ||||||||||
Note. *p < 0.05, **p < 0.01, †p = marginal; W1a = Wave 1, Visit 1; W1b = Wave 1, Visit 2; W2 = Wave 2; a Female= 0, Male= 1; b non-Hispanic/Latino(a)= 0, Hispanic/Latino(a)= 1. Coefficients represent standardized effects. See also Fig. 3. lPFC activations and STG deactivations are at the 3-back level. Task performance = d-prime at the 3-back level.