Table 6.
The best mutations for each residue of the epitopes. The amino acid of the epitope, its position in the source sequence, and its substitute are presented. ΔΔG is presented for each substitution; the negative values indicate the stabilizing mutations. For each prediction, a confidence score typically between 0 to 1 (the higher the better) is provided
| TKNYDSKI | LSLARANS | GQEAAAPA | ||||||
|---|---|---|---|---|---|---|---|---|
| Mutant | ΔΔG_pred | Confidence | Mutant | ΔΔG_pred | Confidence | Mutant | ΔΔG_pred | Confidence |
| T112{D} | −0.741 | 0.966 | L282{W} | 0.022 | 0.944 | G346{Q} | −0.060 | 0.899 |
| K113{W} | 0.886 | 0.818 | S283{W} | −0.762 | 0.925 | Q347{R} | 0.537 | 0.788 |
| N114{E} | 0.342 | 0.830 | L284{M} | 0.045 | 0.896 | E348{R} | 0.254 | 0.823 |
| Y115{W} | 0.027 | 0.916 | A285{M} | −0.613 | 0.968 | A349{E} | −0.418 | 0.969 |
| D116{Y} | 0.187 | 0.857 | R286{M} | −0.344 | 0.856 | A350{E} | −0.237 | 0.909 |
| S117{Q} | 0.128 | 0.853 | A287{W} | −0.177 | 0.950 | A351{Q} | −0.296 | 0.922 |
| K118{W} | 0.568 | 0.762 | N288{W} | −0.709 | 0.906 | P352{W} | 0.133 | 0.870 |
| I119{W} | −0.528 | 0.925 | S289{L} | −0.981 | 0.863 | A353{S} | −0.173 | 0.893 |