Table 2. Univariate and multivariate analyses for predicting the efficacy of concurrent radiotherapy in the training cohort.
| Variable | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||
| The number of chemotherapy cycles administered during CCRT | |||||
| <3 | 1.00 (reference) | 1.00 (reference) | |||
| ≥3 | 0.32 (0.15–0.67) | 0.003 | 0.34 (0.16–0.73) | 0.006 | |
| NSE | |||||
| Normal | 1.00 (reference) | 1.00 (reference) | |||
| Increase | 0.38 (0.17–0.83) | 0.02 | 0.41 (0.18–0.94) | 0.03 | |
| Binary ITH index | |||||
| Low | 1.00 (reference) | 1.00 (reference) | |||
| High | 2.42 (1.14–5.11) | 0.02 | 2.42 (1.14–5.11) | 0.02 | |
CCRT, concurrent chemoradiotherapy; CI, confidence interval; ITH, intra-tumoral heterogeneity; NSE, neuron-specific enolase; OR, odds ratio.