TABLE 5.

Concordance of the Geno4ME LDP and the ORM for identifying gene SNVs/indels in the WGS Validation cohort.

Cohort	WGS validation ORM
N samples	188
Experimental Method	Geno4ME LDP
Reference Method	Hybridization-based NGS
Positive genes confirmed by Reference Method	17/17
Negative genes confirmed by Reference Method	14,382/14,382

Effect size	Percent (95% CI)
Sensitivity	100% (80.5%–100%)
Specificity	100% (100%–100%)
Positive Predictive Value	100% (80.5%–100%)
Negative Predictive Value	100% (100%–100%)