Table 2.
General characteristics of internal validation set.
| Subgroup | Non-hypotension group (n = 108) | Hypotension group (n = 105) | p-value* |
|---|---|---|---|
| Age, Mean ± SD | 32.09 ± 6.18 | 31.58 ± 6.29 | 0.550 |
| Pre BMI, Mean ± SD | 28.57 ± 3.49 | 28.87 ± 3.62 | 0.545 |
| Parity, n (%) | 0.921 | ||
| 0 | 32 (29.63) | 28 (26.67) | |
| 1 | 29 (26.85) | 29 (27.62) | |
| 2 | 21 (19.44) | 19 (18.10) | |
| 3 | 26 (24.07) | 29 (27.62) | |
| PE type, n (%) | <0.001 | ||
| Early-onset | 55 (50.93) | 28 (26.67) | |
| Late-onset | 53 (49.07) | 77 (73.33) | |
| PE severity, n (%) | <0.001 | ||
| Mild | 60 (55.56) | 28 (26.67) | |
| Severe | 48 (44.44) | 77 (73.33) | |
| Platelet, Mean ± SD | 224.44 ± 41.22 | 121.86 ± 22.95 | <0.001 |
| ALT, Mean ± SD | 73.05 ± 29.28 | 65.78 ± 31.09 | 0.081 |
| AST, Mean ± SD | 63.69 ± 27.16 | 63.00 ± 27.83 | 0.856 |
| Sflt 1 Plgf Ratio, Mean ± SD | 51.64 ± 13.37 | 143.83 ± 33.56 | <0.001 |
| Urine protein, Mean ± SD | 865.61 ± 326.72 | 3213.95 ± 1038.32 | <0.001 |
| PAPP A, Mean ± SD | 1.42 ± 0.66 | 1.41 ± 0.66 | 0.954 |
| Baseline SBP, Mean ± SD | 135.18 ± 14.26 | 134.05 ± 14.17 | 0.563 |
| Baseline DBP, Mean ± SD | 87.05 ± 4.61 | 99.42 ± 6.46 | <0.001 |
| Baseline PI, Mean ± SD | 4.54 ± 0.85 | 2.56 ± 0.60 | <0.001 |
| BPV, Mean ± SD | 10.54 ± 2.59 | 18.66 ± 3.46 | <0.001 |
| HRV, Mean ± SD | 50.56 ± 14.74 | 51.16 ± 14.27 | 0.764 |
| Puncture space, n (%) | 0.938 | ||
| L2-3 | 56 (51.85) | 55 (52.38) | |
| L3-4 | 52 (48.15) | 50 (47.62) | |
| Anesthesia level, n (%) | <0.001 | ||
| T10 | 33 (30.56) | 22 (20.95) | |
| T6 | 38 (35.19) | 66 (62.86) | |
| T8 | 37 (34.26) | 17 (16.19) | |
| Preload fluid, Mean ± SD | 871.79 ± 68.61 | 886.07 ± 68.23 | 0.129 |
| LA dose, Mean ± SD | 9.61 ± 0.89 | 12.45 ± 1.04 | <0.001 |
| Time to incision, Mean ± SD | 14.66 ± 6.16 | 15.27 ± 6.14 | 0.470 |
| Gestational weeks, Mean ± SD | 33.00 ± 3.33 | 33.70 ± 3.45 | 0.136 |
| Fetus weight, Mean ± SD | 2817.92 ± 357.63 | 3139.77 ± 358.29 | <0.001 |
| UA SD ratio, Mean ± SD | 2.64 ± 0.34 | 3.74 ± 0.42 | <0.001 |
| NST result, n (%) | 0.793 | ||
| Non-reactive | 20 (18.52) | 18 (17.14) | |
| Reactive | 88 (81.48) | 87 (82.86) | |
| SBP min, Mean ± SD | 105.02 ± 8.92 | 76.12 ± 5.71 | <0.001 |
| Vasopressor total, Mean ± SD | 86.27 ± 42.12 | 539.48 ± 170.31 | <0.001 |
| UA pH, Mean ± SD | 7.30 ± 0.06 | 7.20 ± 0.06 | <0.001 |
| Fetal acidosis, n (%) | <0.001 | ||
| No | 108 (100.00) | 48 (45.71) | |
| Yes | 0 (0.00) | 57 (54.29) |
Data are presented as mean ± standard deviation, or number (%). SD, standard deviation; BMI, body mass index; ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; BPV, Blood Pressure Variability; DBP, Diastolic Blood Pressure; HRV, Heart Rate Variability; LA, Local Anesthetic; NST, Non-Stress Test; PAPP-A, Pregnancy-Associated Plasma Protein-A; PE, Preeclampsia; PI, Perfusion Index; PlGF, Placental Growth Factor; SBP, Systolic Blood Pressure; SD (in UA SD ratio): Systolic/Diastolic; sFlt-1, soluble fms-like tyrosine kinase-1; UA, Umbilical Artery.