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. 2001 Aug 15;20(16):4325–4331. doi: 10.1093/emboj/20.16.4325

Table II. Bacterial and viral proteins not related to Bcl-2 acting on mitochondria.

Microorganism Observation References
Cytomegalovirus vMIA (anti-apoptotic) interacts with ANT (not VDAC) and prevents MMP Goldmacher et al. (1999); Colberg-Poley et al. (2000)
Helicobacter pylori N-terminal cleavage product (p34) of vacuolating cytotoxin (Vac A) (pro-apoptotic) translocates to mitochondria and releases cytochrome c in a Bcl-2-inhibitable fashion Galmiche et al. (2000)
Hepatitis B virus HBV-X (pro-apoptotic) translocates to mitochondria, interacting with VDAC-3 Rahmani et al. (2000)
HIV-1 Vpr (pro-apoptotic) interacts with ANT and induces MMP, both in intact cells and in mitochondria in vitro; Tat (pro-apoptotic) translocates to mitochondria Jacotot et al. (2000); Macho et al. (1999)
HTLV-1 p13II protein (pro-apoptotic) interacts with mitochondria Ciminale et al. (1999)
Myxoma virus M11L (anti-apoptotic) translocates to mitochondria and prevents MMP Everett et al. (2000)
Neisseria meningitidis porin B (pro-apoptotic) translocates to mitochondria; porin B causes isolated mitochondria to release cytochrome c and to swell Muller et al. (2000)
Neisseria gonorrhoeae porin B (anti-apoptotic) translocates to mitochondria, where it interacts with VDAC; porin B prevents MMP Massari et al. (2000)