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. 2005 Oct 11;33(18):5771–5780. doi: 10.1093/nar/gki865

Table 3.

Coupling efficiency in chemical synthesis of several Oxa-ODNs

Sequence Position Coupling yield
e        d c b        a aba bc (%) cd (%) dea aea
COG-18 5′-TCT CTT CCO GCC TAC GAT-3′ 96.96% ± 2.44% 93.39 97.82 96.92 ± 2.59% 96.70 ± 2.52%
TOA-18 5′-TCT CTT CTO ACC TAC GAT-3′ 96.58% ± 2.23% 96.28 96.60 97.64 ± 1.19% 97.02 ± 1.79%
GOC-18 5′-TCT CTT CGO CCC TAC GAT-3′ 97.09% ± 2.30% 98.06 97.28 96.59 ± 1.26% 97.16 ± 2.23%
AOT-18 5′-TCT CTT CAO TCC TAC GAT-3′ 97.28% ± 1.86% 99.09 97.60 97.42 ± 1.32% 97.40 ± 1.86%

aAverage step-wise coupling yield.