Table 5.
Analysis of baseline risk factors for death (LT competing risk) in the elective TIPS group.
| Univariate analysis for death or LT in pTIPS group sHR [95% CI], p value |
p value | |
|---|---|---|
| Age | 1.07 [1.02-1.12] | 0.01 |
| Type 2 diabetes | 1.50 [0.80-2.78] | 0.20 |
| Previous cardiac disease | 2.88 [1.40-5.92] | 0.004 |
| Bilirubin | 1.01 [1.00-1.03] | 0.17 |
| Platelets count | 1.00 [1.00-1.00] | 0.28 |
| Albumin | 0.97 [0.85-1.06] | 0.56 |
| Baseline ammonia | 1.01[1.00-1.01] | 0.18 |
| Creatinine | 1.01 [1.00-1.01] | <0.001 |
| MELD score | 1.09 [1.00-1.18] | 0.048 |
| Child-Pugh score | 1.08 [0.87-1.33] | 0.48 |
| HVPG | 1.04 [0.94-1.14] | 0.47 |
| PPG | 1.01 [0.90-1.13] | 0.87 |
| OHE after TIPS | 3.40 [1.57-7.36] | 0.002 |
| Refractory OHE after TIPS | 5.14 [2.42-10.90] | <0.001 |
| Model 1 |
Multivariate analysis for death or LT in pTIPS group sHR [95% CI], p value |
p value |
| Age | 1.06 [1.01-1.12] | 0.03 |
| MELD | 1.10 [1.01-1.29] | 0.04 |
| OHE after TIPS | 2.94 [1.21-7.11] | 0.017 |
| Model 2 | ||
| Age | 1.05 [0.99-1.11] | 0.08 |
| MELD | 1.11 [1.02-1.24] | 0.02 |
| Refractory OHE after TIPS | 4.92 [2.25-10.8] | <0.001 |
Bolded values indicate statistically significant differences (p <0.05) (Fine and Gray models). HVPG, hepatic venous pressure gradient; MELD, model for end-stage liver disease; OHE, overt hepatic encephalopathy; PPG, portal pressure gradient; sHR, subdistribution hazard ratio; TIPS, transjugular intrahepatic portosystemic shunt.