Table 2.
Results by model and outcome class for breast cancer validation and test datasets.
| Datasets and metrics | Bio+ClinicalBERT | Clinical-BigBird | Clinical-Longformer | |||||||||||||||
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|
2-class | 3-class | 2-class | 3-class | 2-class | 3-class | ||||||||||||
|
|
Head | Tail | Head and tail | Head | Tail | Head and tail |
|
|
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| Validation | ||||||||||||||||||
|
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Sensitivity, % | 71.9 | 71.2 | 80.7 | 79.0 | 84.2 | 74.0 | 84.0 | 86.0 | 76.7 | 86.7 a | |||||||
|
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PPVb, % | 85.1 | 90.5 | 86.8 | 88.1 | 84.7 | 87.5 | 88.7 | 84.2 | 93.0 | 84.1 | |||||||
|
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AUCc | 0.96 | 0.97 | 0.97 | 0.97 | 0.98 | 0.97 | 0.98 | 0.98 | 0.97 | 0.98 | |||||||
|
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Scaled Brier score | 0.60 | 0.62 | 0.68 | 0.68 | 0.70 | 0.64 | 0.73 | 0.71 | 0.72 | 0.72 | |||||||
|
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Charts reduced, % | 86.2 | 87.2 | 84.8 | 85.4 | 83.8 | 86.2 | 84.5 | 83.3 | 86.5 | 83.2 | |||||||
| Test | ||||||||||||||||||
|
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Sensitivity, % | 84.5 | 76.6 | 87.1 | 82.3 | 85.9 | 82.5 | 86.6 | 93.6 | 94.3 | 93.6 | |||||||
|
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PPV, % | 85.1 | 87.1 | 81.8 | 85.5 | 80.6 | 83.6 | 92.3 | 77.9 | 78.7 | 81.6 | |||||||
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AUC | 0.98 | 0.97 | 0.98 | 0.98 | 0.98 | 0.98 | 0.99 | 0.99 | 0.99 | 0.99 | |||||||
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Scaled Brier score | 0.71 | 0.66 | 0.69 | 0.70 | 0.68 | 0.68 | 0.79 | 0.72 | 0.70 | 0.76 | |||||||
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Charts reduced, % | 87.1 | 88.6 | 86.2 | 87.5 | 86.2 | 87.2 | 87.8 | 84.4 | 84.4 | 85.1 | |||||||
aItalicization indicates the highest value.
bPPV: positive predictive value.
cAUC: area under the curve.