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. 2025 Oct 13;4:e63767. doi: 10.2196/63767

Table 4.

Results by model and outcome class for colorectal cancer validation and test datasets.

Datasets and metrics Bio+ClinicalBERT Clinical-BigBird Clinical-Longformer

2-class 3-class 2-class 3-class 3-class 3-class

Head Tail Head and tail Head Tail Head and tail



Validation

Sensitivity, % 80.9 78.5 82.0 86.4 79.9 80.4 82.4 88.4 81.0 91.3 a

PPVb, % 88.3 85.2 88.7 84.0 80.3 87.1 88.3 87.4 91.8 82.4

AUCc 0.98 0.98 0.97 0.99 0.98 0.98 0.98 0.99 0.98 0.99

Scaled Brier score 0.72 0.67 0.73 0.73 0.66 0.72 0.75 0.77 0.76 0.75

Charts reduced, % 88.6 88.6 88.5 87.2 87.6 88.5 88.4 87.4 89 86.2
Test

Sensitivity, % 74.1 62.8 71.9 77.0 63.7 69.7 78.5 75.4 73.1 78.9

PPV, % 79.8 81.1 82.4 72.9 82.4 82.9 81.6 82.0 86.3 81.9

AUC 0.96 0.95 0.96 0.96 0.95 0.96 0.97 0.96 0.96 0.97

Scaled Brier score 0.56 0.49 0.54 0.61 0.54 0.58 0.63 0.61 0.65 0.64

Charts reduced, % 90.1 91.7 90.7 88.7 91.8 91.0 89.7 90.2 91.0 89.7

aItalicization indicates the highest value.

bPPV: positive predictive value.

cAUC: area under the curve.