Table 4.
Results by model and outcome class for colorectal cancer validation and test datasets.
| Datasets and metrics | Bio+ClinicalBERT | Clinical-BigBird | Clinical-Longformer | |||||||||||||||
|
|
2-class | 3-class | 2-class | 3-class | 3-class | 3-class | ||||||||||||
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Head | Tail | Head and tail | Head | Tail | Head and tail |
|
|
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|
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| Validation | ||||||||||||||||||
|
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Sensitivity, % | 80.9 | 78.5 | 82.0 | 86.4 | 79.9 | 80.4 | 82.4 | 88.4 | 81.0 | 91.3 a | |||||||
|
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PPVb, % | 88.3 | 85.2 | 88.7 | 84.0 | 80.3 | 87.1 | 88.3 | 87.4 | 91.8 | 82.4 | |||||||
|
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AUCc | 0.98 | 0.98 | 0.97 | 0.99 | 0.98 | 0.98 | 0.98 | 0.99 | 0.98 | 0.99 | |||||||
|
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Scaled Brier score | 0.72 | 0.67 | 0.73 | 0.73 | 0.66 | 0.72 | 0.75 | 0.77 | 0.76 | 0.75 | |||||||
|
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Charts reduced, % | 88.6 | 88.6 | 88.5 | 87.2 | 87.6 | 88.5 | 88.4 | 87.4 | 89 | 86.2 | |||||||
| Test | ||||||||||||||||||
|
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Sensitivity, % | 74.1 | 62.8 | 71.9 | 77.0 | 63.7 | 69.7 | 78.5 | 75.4 | 73.1 | 78.9 | |||||||
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PPV, % | 79.8 | 81.1 | 82.4 | 72.9 | 82.4 | 82.9 | 81.6 | 82.0 | 86.3 | 81.9 | |||||||
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AUC | 0.96 | 0.95 | 0.96 | 0.96 | 0.95 | 0.96 | 0.97 | 0.96 | 0.96 | 0.97 | |||||||
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Scaled Brier score | 0.56 | 0.49 | 0.54 | 0.61 | 0.54 | 0.58 | 0.63 | 0.61 | 0.65 | 0.64 | |||||||
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Charts reduced, % | 90.1 | 91.7 | 90.7 | 88.7 | 91.8 | 91.0 | 89.7 | 90.2 | 91.0 | 89.7 | |||||||
aItalicization indicates the highest value.
bPPV: positive predictive value.
cAUC: area under the curve.