Table 6.
Results by model and outcome class for the model applied to different cancer sites.
| Model, test dataset, and metrics | Bio+ClinicalBERT | Clinical-BigBird | Clinical-Longformer | |||||||||||||||||||||||
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2-class | 3-class | 2-class | 3-class | 2-class | 3-class | ||||||||||||||||||||
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Head | Tail | Head and tail | Head | Tail | Head and tail |
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| Colorectal cancer model applied to breast cancer test dataset | ||||||||||||||||||||||||||
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Sensitivity, % | 76.3 | 76.8 | 76.3 | 76.1 | 75.9 | 73.0 | 84.4 a | 83.8 | 77.1 | 82.0 | |||||||||||||||
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PPVb, % | 83.9 | 85.1 | 81.6 | 78.3 | 87.0 | 83.3 | 81.4 | 83.3 | 87.0 | 82.7 | |||||||||||||||
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AUCc | 0.96 | 0.96 | 0.94 | 0.95 | 0.95 | 0.95 | 0.97 | 0.97 | 0.95 | 0.96 | |||||||||||||||
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Scaled Brier score | 0.62 | 0.63 | 0.61 | 0.58 | 0.65 | 0.60 | 0.65 | 0.68 | 0.69 | 0.66 | |||||||||||||||
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Charts reduced, % | 88.2 | 88.3 | 87.9 | 87.4 | 88.7 | 88.6 | 86.6 | 86.9 | 88.5 | 87.1 | |||||||||||||||
| Breast cancer model applied to colorectal cancer test dataset | ||||||||||||||||||||||||||
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Sensitivity, % | 69.4 | 63.4 | 75.4 | 70.7 | 63.0 | 70.3 | 68.5 | 83.6 | 86.8 | 82.4 | |||||||||||||||
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PPV, % | 80.6 | 82.5 | 76.3 | 80.9 | 82.9 | 77.7 | 86.8 | 74.6 | 70.8 | 74.0 | |||||||||||||||
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AUC | 0.97 | 0.96 | 0.97 | 0.97 | 0.96 | 0.97 | 0.97 | 0.98 | 0.98 | 0.98 | |||||||||||||||
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Scaled Brier score | 0.55 | 0.52 | 0.55 | 0.57 | 0.55 | 0.55 | 0.58 | 0.61 | 0.55 | 0.61 | |||||||||||||||
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Charts reduced, % | 90.8 | 91.8 | 89.5 | 90.7 | 91.9 | 90.4 | 91.2 | 88.1 | 86.9 | 88.1 | |||||||||||||||
aItalicization indicates the highest value.
bPPV: positive predictive value.
cAUC: area under the curve.