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. 2025 Sep 29;47(10):804. doi: 10.3390/cimb47100804
CRC colorectal cancer
TCGA The Cancer Genome Atlas
GEO Gene Expression Omnibus
GSEA gene set enrichment analysis
GO Gene Ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
ssGSEA single-sample GSEA
LASSO least absolute shrinkage and selection operator
qRT-PCR quantitative real-time polymerase chain reaction
IHC immunohistochemistry
TME tumor microenvironment
TAMs tumor-associated macrophages
MMPs matrix metalloproteinases
PD-L1 programmed cell death 1 ligand 1
scRNA-seq single-cell RNA sequencing
TMB tumor mutation burden
TIDE Tumor Immune Dysfunction and Exclusion
UMI unique molecular identifier
VST variance stabilizing transformation
UMAP uniform manifold approximation and projection
AUC area under the curve
MIF macrophage migration inhibitory factor
SPHK1 sphingosine kinase 1
VSIG4 v-set and immunoglobulin domain-containing 4
FCGR2B Fc gamma receptor IIb
FPR2 formyl peptide receptor 2
AT-SPM aspirin-triggered specialized proresolving mediators