| CRC | colorectal cancer |
| TCGA | The Cancer Genome Atlas |
| GEO | Gene Expression Omnibus |
| GSEA | gene set enrichment analysis |
| GO | Gene Ontology |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| ssGSEA | single-sample GSEA |
| LASSO | least absolute shrinkage and selection operator |
| qRT-PCR | quantitative real-time polymerase chain reaction |
| IHC | immunohistochemistry |
| TME | tumor microenvironment |
| TAMs | tumor-associated macrophages |
| MMPs | matrix metalloproteinases |
| PD-L1 | programmed cell death 1 ligand 1 |
| scRNA-seq | single-cell RNA sequencing |
| TMB | tumor mutation burden |
| TIDE | Tumor Immune Dysfunction and Exclusion |
| UMI | unique molecular identifier |
| VST | variance stabilizing transformation |
| UMAP | uniform manifold approximation and projection |
| AUC | area under the curve |
| MIF | macrophage migration inhibitory factor |
| SPHK1 | sphingosine kinase 1 |
| VSIG4 | v-set and immunoglobulin domain-containing 4 |
| FCGR2B | Fc gamma receptor IIb |
| FPR2 | formyl peptide receptor 2 |
| AT-SPM | aspirin-triggered specialized proresolving mediators |