NSCLC	Non-small cell lung cancer
HER2	Human epidermal growth factor receptor 2
ERBB2	erb-b2 receptor tyrosine kinase 2
TKI	Tyrosine kinase inhibitors
ADC	Antibody-drug conjugates
EGFR	Epidermal growth factor receptor
FISH	Fluorescence in situ hybridization
IHC	Immunohistochemistry
RTK	Receptor tyrosine kinase
ASCO/CAP	American Society of Clinical Oncology and the College of American Pathologists
ORR	Objective response rate
DCR	Disease control rate
PFS	Progression-free survival
OS	Overall survival
TRAE	Treatment-related adverse events
MBC	Metastatic breast cancer
T-DM1	Trastuzumab-emtansine
T-DXd	Trastuzumab-deruxtecan
NGS	Next-generation sequencing
ER	Estrogen receptor
ILD	Interstitial lung disease
ICIs	Immune checkpoint inhibitors
bsAbs	bispecific antibodies
ECD	extracellular domains