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. 2025 Oct 10;26(20):9867. doi: 10.3390/ijms26209867
ADSC Adipose-derived stem cells
AKT/PKβ Serine/threonine kinase or protein kinase β
AMPK Adenosine monophosphate-activated protein kinase
AT Adipose tissue
ATP Adenosine triphosphate
BAT Brown adipose tissue
Breg Regulatory B cell
BMI Body mass index
BS Bariatric surgery
CD Cluster of differentiation
CD3+ Total T lymphocyte
CD4+ T helper lymphocyte
CD4+CD45RA+ Naive T helper lymphocyte
CD4+CD45RO+ Memory T helper lymphocyte
CD4+CD62− Effector help T lymphocyte
CD8+/CTLs Cytotoxic T lymphocytes
CD8+CD28− Effector cytotoxic T lymphocyte
CD8+CD45RA+ Naive cytotoxic T lymphocyte
CD8+CD45RO+ Memory cytotoxic T lymphocyte
COX-2 Ciclooxygenase-2
CXCL Chemokine (C-X-C motif) ligand
Cells/µL Counting or absolute number
CRP C-reactive protein
DAMP Danger-associated molecular pattern
DNA Deoxyribonucleic acid
EV Extracellular vesicles
ERK Extracellular signal-regulated kinases
FGF21 Circulating protein belonging to the human FGF superfamily
FFM Fat-free mass
FFAR Free fatty acid receptor
GM Gut microbiota
GPCRs G protein-coupled receptors
GLP-1 Glucagon-like peptide-1
HDL-c High-density lipoprotein cholesterol
HbA1c Glycated hemoglobin
HIF-1 Hypoxia-inducible factor 1
HIF-1α Hypoxia-inducible factor 1 alpha
HIF-1β Hypoxia-inducible factor 1 beta
HMGB1 High-mobility group box 1
HOMA-IR Homeostatic model assessment of insulin resistance
HRE Hypoxia response element
ICAM-1 Intercellular adhesion molecule-1
IFN-γ Interferon gamma
Ig Immunoglobulin
IgA Immunoglobulin A
IgG Immunoglobulin G
IgM Immunoglobulin M
IGFBP-2 Insulin-like growth factor-binding protein 2
IGFBP7 Insulin-like growth factor binding protein-7
IKK Ikappaβ kinase
IkβK Inhibition of IκB kinase
IL Interleukin
IL-1β interleukin-1 beta
IL-7R Interleukin 7 receptor
ILCs Innate lymphoid cells
IR Insulin resistance
IRS-1 Insulin receptor substrate 1
IRS-2 Insulin receptor substrate 2
Iκβ Ikappaβ
Jak3 Janus kinase 3
JNK C-Jun N-terminal kinase
LBD Laparoscopic biliopancreatic diversion
LDL-c Low-density lipoprotein cholesterol
LPS Lipopolysaccharide
LRYGB Laparoscopic Roux-en-Y gastric bypass
LSG Laparoscopic sleeve gastrectomy
MAPK p38 mitogen-activated protein kinase
MASLD Metabolic dysfunction-associated steatosis liver disease
M1 Pro-inflammatory macrophage
M2 Anti-inflammatory macrophage
MCP-1/CCL2 Monocyte chemoattractant protein-1
MHC Major histocompatibility complex
MIOR Metainflammation-related obesity
MS Metabolic syndrome
mTOR Mammalian target of rapamycin
NAD+ Nicotinamide adenine dinucleotide
NADP Nicotinamide adenine dinucleotide phosphate
NF-κβ Nuclear factor kappa-light-chain-enhancer of activated β cell
NK Natural killers
NKG2D Natural killer group 2 member D
NLRs NOD-like receptors
NLRP3 NLR family pyrin domain containing 3 or inflammasome
NOTCH1 Neurogenic locus notch homolog protein 1
OGM Obesogenic gut
OXPHOS Oxidative phosphorylation
PAI-1 Plasminogen activator inhibitor type-1
PAMPs Pathogen-associated molecular patterns
PI3K-Akt Phosphoinositide-3-kinase-protein kinase B
PUFAs Polyunsaturated fatty acids
PVAT Perivascular adipose tissue
ROS Reactive oxygen species
SASP Senescence-associated secretory phenotype
SIRT1 Sirtuin-1 deacetylase
SCFAs Short-chain fatty acids
SPMs Specialized pro-resolving mediators
REBPs Sterol regulatory element-binding proteins
TBF Total body fat
T2D Type 2 diabetes
TCR T cell receptor
TGF-β Transforming growth factor beta
Th0 Naive T cells
TLRs Toll-like receptors
TLR2 Toll-like receptor 2
TLR4 Toll-like receptor 4
TNF-α Tumor necrosis factor alpha
Tregs Regulatory T cells
VAT Visceral adipose tissue
VHL Hippel–Lindau
VF Visceral fat
WAT White adipose tissue