AKT	serine/threonine (Ser/Thr) kinase
ASO	antisense oligonucleotide
ATP	adenosine triphosphate
DDIT4	DNA-damage-inducible transcript 4
DEGs	differentially expressed genes
DIO	diet-induced obesity
DMD	Duchenne muscular dystrophy
FAO	fatty acid oxidation
FOXO	forkhead box O
GAS	gastrocnemius
H&E	Hematoxylin and eosin
HFD	high-fat diet
HSkMC	human skeletal muscle cells
IMAT	intramuscular adipose tissue
MAP1LC3B/LC3	microtubule-associated protein 1 light chain 3 beta
LNA	locked nucleic acid
MetS	metabolic syndrome
miR-22	microRNA-22
miRNAs	microRNAs
mTOR	mammalian target of rapamycin
mTORC1	mammalian target of rapamycin complex 1
MYH	myosin heavy chain
MyoD1	myoblast determination protein 1
MYOG	myogenin
myomiRs	muscle-enriched microRNAs
NRF1	nuclear respiratory factor 1
OPA1	optic atrophy 1
ORO	oil red O
PGC-1α	peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PPARGC1a	peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PSR	picrosirius red
PTEN	phosphatase and tensin homolog
qRT-PCR	quantitative real-time polymerase chain reaction
SEM	standard error of the mean
UTR	untranslated region
β-gal	beta-galactosidase
%CFB	percentage of change from baseline