AAV	Adeno-associated viruses
ACSL4	Acyl-CoA synthetase long chain family member 4
ADAMTS	A disintegrin and metalloproteinase with thrombospondin motifs
AF	Annulus fibrosus
AGE	Advanced glycation end-product
AIM2	Absent in melanoma 2
AKAP150	A-kinase anchoring protein 150
AMPK	AMP-activated protein kinase
ANGPTL4	Angiopoietin-like 4
ASC	Apoptosis-associated speck-like protein containing a CARD
Atg	Autophagy-related protein
BDNF	Brain-derived neurotrophic factor
BMP	Bone morphogenetic protein
BMP-7	Bone morphogenetic protein-7
β-NGF	β-nerve growth factor
CA HIF-1α	Constitutively active form of HIF-1α
CCL	Chemokine ligand
CEP	Cartilage endplates
C/EBP	CCAAT-enhancer-binding protein
CGRP	Calcitonin gene-related peptide
COX-2	Cyclooxygenase-2
DAMPs	Damage-associated molecular patterns
DFO	Deferoxamine
DFP	Deferiprone
DFX	Deferasirox
ECM	Extracellular matrix
EGF	Epidermal growth factor
ER	Endoplasmic reticulum
ESCRT	Endosomal sorting complex required for transport
FAK	Focal adhesion kinase
FasL	Fas ligand
Fe2+	Ferrous iron
Fer-1	Ferrostatin-1
FPN/SLC40A1	Ferroportin
GDF	Growth differentiation factor
GF	Growth factor
Glut-1	Glucose transporter 1
Glut-3	Glucose transporter 3
GM-CSF	Granulocyte-macrophage colony stimulating factor
GPX4	Glutathione peroxidase 4
GSDMD	Gasdermin D
GSDMD-NT	N-terminal pore-forming GSDMD fragment
GSDME	Gasdermin E
GSH	Glutathione
HIF-1α	Hypoxia-inducible factor-1 alpha
HIF-2α	Hypoxia inducible factor 2α
HO-1	Heme oxygenase 1
HTRA1	High-temperature requirement protein A1
IFN-γ	Interferon-γ
IGF-1	Insulin-like growth factor-1
IL	Interleukin
iNOS	Inducible nitric oxide synthase
IRF1	Interferon regulatory factor 1
IVD	Intervertebral disc
IVDD	Intervertebral disc degeneration
LC3-II	LC3-phosphatidylethanolamine conjugate
Lip-1	Liproxstatin-1
LOX	Lipoxygenase
LPCAT3	Lysophosphatidylcholine acyltransferase 3
MAPK	Mitogen-activated protein kinase
miRNA	Micro ribonucleic acid
MLKL	Mixed lineage kinase domain-like protein
MMP	Matrix metalloproteinase
MSC	Mesenchymal stem cell
mTOR	Mammalian/Mechanistic target of rapamycin
mTORC1	Mammalian target of rapamycin complex 1
NC	Notochordal cell
NF-κB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NGF	Nerve growth factor
NK	Natural killer
NLRC4	NLR family CARD domain-containing protein 4
NLRP3	NLR family pyrin domain containing 3
NO	Nitric oxide
NP	Nucleus pulposus
NR4A1	Nuclear receptor 4A1
NSAID	Non-steroidal anti-inflammatory drug
OPN	Osteopontin
PAMP	Pathogen-associated molecular pattern
PDGF	Platelet-derived growth factor
PGE2	Prostaglandin E2
PRP	Platelet-rich plasma
PUFA	Polyunsaturated fatty acid
Rb	Retinoblastoma protein
RIPK1	Receptor-interacting serine/threonine-protein kinase 1
RIPK3	Receptor-interacting serine/threonine-protein kinase 3
RNAi	RNA interference
ROS	Reactive oxygen species
SASP	Senescence-associated secretory phenotype
SA-β-gal	Senescence-associated β-galactosidase
SIPS	Stress-induced premature senescence
SLRP	Small leucine-rich proteoglycan
SOD	Superoxide dismutase
STAT3	Signal transducer and activator of transcription 3
sTNF-α	Soluble tumor necrosis factor-alpha
TACE	Tumor necrosis factor-alpha converting enzyme
TAZ	Transcriptional co-activator with PDZ-binding motif
TDR	Total disc replacement
TFR1	Transferrin receptor
TGF-β	Transforming growth factor-beta
TIMP	Tissue inhibitor of metalloproteinase
TLR4	Toll-like receptor 4
tmTNF-α	Transmembrane tumor necrosis factor-alpha
TNFR1	Tumor necrosis factor receptor 1
TNFR2	Tumor necrosis factor receptor 2
TNF-α	Tumor necrosis factor-alpha
TRPV4	Transient receptor potential cation channel subfamily V member 4
ULK1	Unc-51-like kinase 1
UTMD	Ultrasound-targeted microbubble destruction
VEGF	Vascular endothelial growth factor
YAP	Yes-associated protein