APC	Activated protein C
MD	Molecular dynamics
PDB	Protein Data Bank
RMSD	Root mean square deviation
RMSF	Root mean square fluctuation
MM/PBSA	Mechanics/Poisson–Boltzmann surface area
HPLC	High-performance liquid chromatography
BLI	Biolayer interferometry
ICK	Inhibitor cystine knot
PRT	Plasma recalcification time
PT	Prothrombin time
APTT	Activated partial thromboplastin time
HE staining	Hematoxylin–eosin staining
NGS	Next-generation sequencing
LSP	Laser speckle perfusion
SPPS	Solid-phase peptide synthesis
TFA	Trifluoroacetic acid
CCK-8	Cell Counting Kit 8
CPS	Cortical photothrombosis stroke
IVC	Inferior vena cava
DVT	Deep vein thrombosis
ANOVA	One-way analysis of variance
SEM	Standard error of the mean