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. 2025 Oct 16;18(10):1564. doi: 10.3390/ph18101564
4-AP 4-aminopyridine
5-HT Serotonin receptors
AC Adenylate cyclase
ACh Acetylcholine
ADRA Adrenergic receptors
BK Large-conductance calcium-activated potassium channels
cGMP Cyclic guanosine monophosphate
COX-2 Cyclooxygenase-2
CREB cAMP response element-binding protein
DAG diacylglycerol
EC50 half-maximal effective concentration
eNOS Endothelial nitric oxide synthase
GI Gastrointestinal
IBS Irritable bowel syndrome
IK Intermediate-conductance calcium-activated potassium channels
IL Interleukin
iNOS Inducible nitric oxide synthase
IP3 Inositol trisphosphate
IP3R Inositol trisphosphate potassium receptor
KATP ATP-sensitive potassium channels
LES Lower esophageal sphincter
L-NAME N(G)-nitro-L-arginine methyl ester
M2, M3 Muscarinic acetylcholine receptors
MLC20 20 kDa regulatory light chains
MLCK Myosin light chain kinase
MLCP Myosin light chain phosphatase
MPO Myeloperoxidase
NMR Nuclear magnetic resonance spectroscopy
NO Nitric oxide
NOS Nitric oxide synthase
ODQ NO-sensitive guanylyl cyclase
PIP2 phosphatidylinositol 4,5-bisphosphate
PKA Protein kinase A
PKC Protein kinase C
PKG Protein kinase G
PLB phospholamban
PLCβ phospholipase C beta
ROCK Rho-associated protein kinase
RyR Ryanodine receptor
SERCA2a sarco/endoplasmic reticulum Ca2+-ATPase 2a
sGC Soluble guanylate cyclase
SK Small-conductance calcium-activated potassium channels
SR Sarcoplasmic reticulum
TEA Triethylamine
TNF Tumor necrosis factor
TTX Tetrodotoxin
VGCC Voltage-gated calcium channel