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. 2025 Oct 15;16:1658897. doi: 10.3389/fimmu.2025.1658897

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Copyright © 2025 Liu, Zhang, Dong, Jiang, Xie and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three-panel image with data visualizations. Panel A shows a line graph of coefficients versus log lambda, illustrating paths of shrinking variables. Panel B features a line graph of partial likelihood deviance versus log lambda, with error bars and an optimal lambda indicated by a red dot. Panel C is a table with hazard ratios for six variables (AKT1S1, CX3CL1, DDIT4, DECR1, KIF20A, PCDH7), each with sample size 472. The hazard ratios range from 0.87 to 1.53, with p-values indicating statistical significance. — Construction of the prognostic model for DFRGs. (A) LASSO regression analysis. (B) λ selection diagram. (C) Forest plot of multivariate Cox regression.