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Fig. 1. The effect of H2S in vivo on mean arterial blood pressure (BP) and heart rate of rats. (A) Intravenous injection of H2S induced significant decrease in BP. This effect was mimicked by intravenous injection of pinacidil (2.8 µmol/kg) and antagonized by a prior intravenous injection of glibenclamide (2.8 µmol/kg). (B) Effect of H2S on rat heart rate. Heart rate was recorded 30 s after intravenous injection of PBS (control), H2S or pinacidil. *P < 0.05 compared with control.
