Fig. 8. A possible model for the interactions between EAT-2, SH2D1A and the four cell surface receptors at the interface of B lymphocytes, macrophages (Mφ) and T cells. The receptor–ligand interactions of CD48/CD244 (Brown et al., 1998) and CD150/CD150 (Punnonen et al., 1997; Mavaddat et al., 2000) have been reported.