Skip to main content
Patient Safety in Surgery logoLink to Patient Safety in Surgery
. 2025 Oct 29;19:31. doi: 10.1186/s13037-025-00454-y

Smart technologies and digital innovations for improving perioperative patient safety: a review

Saeid Amini Rarani 1,
PMCID: PMC12573887  PMID: 41163177

Abstract

Smart digital technologies are rapidly transforming perioperative care through tools such as clinical decision support systems, wearable sensors, and electronic checklists. Despite growing adoption, their specific impact on patient safety in the operating room remains insufficiently understood. This narrative review explores recent advancements in perioperative digital health and examines how innovations like AI-assisted systems, electronic WHO checklists, and physiological monitoring wearables contribute to safer surgical care. The evidence suggests that these tools can enhance complication detection, protocol adherence, and team communication. However, their effectiveness is tempered by challenges including alert fatigue, fragmented data systems, and added digital workload for healthcare staff. To realize their full potential, future implementations must prioritize usability, interoperability, and seamless workflow integration. Rigorous clinical trials and cost-effectiveness studies are also needed to establish the true value of smart technologies in improving surgical patient outcomes.

Keywords: Perioperative care, Patient safety, Digital health, Wearable devices, AI decision support, Surgical checklists

Background

In recent years, healthcare systems worldwide have undergone a seismic shift toward digital transformation. From electronic health records and telemedicine to artificial intelligence (AI)–powered diagnostics and wearable health monitors, these innovations promise to revolutionize how care is delivered [1]. While much of this evolution has focused on chronic disease management or outpatient care, the application of digital health tools in high-risk, high-acuity environments such as the operating room (OR) remains relatively underexplored [2].

Surgical care, particularly in the perioperative period, presents a unique set of challenges. It is a time-sensitive, high-pressure environment where interdisciplinary collaboration, rapid clinical decision-making, and strict protocol adherence are critical [3]. Despite advances in surgical techniques and anesthesia, adverse events continue to occur. According to the World Health Organization, complications from surgical care are responsible for over 7 million disabling complications and at least 1 million deaths globally each year many of which are preventable through better communication, teamwork, and monitoring protocols [4].

This is where digital health enters the conversation not merely as a futuristic tool, but as a present necessity. Devices such as wearable sensors can now monitor vital signs in real time and alert clinicians to early signs of deterioration [5]. AI-powered clinical decision support systems can help anesthesiologists anticipate complications based on patient-specific risk models. Digital platforms can streamline team communication and even automate safety protocols such as timeouts and instrument counts [6, 7].

However, introducing smart technology into the operating room is not without its own risks. Concerns about alert fatigue, over-reliance on automation, data overload, and the disruption of clinical workflows are well-documented [8]. Additionally, many tools are developed outside of clinical settings, lacking validation in real-world surgical environments. This raises critical questions: Are these innovations improving safety, or are they introducing new, hidden risks? [9].

This narrative review aims to bridge this gap by examining recent innovations in digital health that target perioperative patient safety. We explore technologies ranging from wearable devices and digital checklists to AI-based decision support and robotics. We also consider ethical concerns, implementation barriers, and the limited but growing evidence base surrounding these tools. By synthesizing current knowledge and highlighting opportunities and limitations, we hope to inform both clinicians and policymakers on how to navigate the digital shift in surgical safety.

As we stand at the intersection of technology and critical care, understanding how to harness digital health not just for efficiency, but for genuine safety improvement, is essential. The operating room of the future is being built now and safety must be its foundation.

AI-powered decision support: predicting the unpredictable

AI has rapidly emerged as a critical tool for improving decision-making in complex, high-risk environments none more so than the operating room. In the perioperative setting, AI-based clinical decision support systems (CDSS) are being designed to assist surgeons, anesthesiologists, and nurses by analyzing large volumes of data to predict patient risks, recommend interventions, and reduce human error [10, 11].

Machine learning algorithms trained on vast datasets of surgical cases can identify patterns that precede complications such as surgical site infections, bleeding, or anesthesia-related adverse events. For example, models using intraoperative hemodynamic and ventilatory data have shown promise in predicting hypotensive episodes or desaturation events minutes before they occur giving teams a valuable head start [12].

Beyond prediction, AI can also provide recommendation-based decision support such as flagging drug interactions, suggesting antibiotic regimens based on microbiome data, or even guiding fluid resuscitation protocols. AI systems integrated with electronic health records can personalize recommendations based on a patient’s comorbidities, lab values, and procedure-specific risks [13, 14].

For patient safety, this represents a significant leap forward: clinicians are no longer solely reactive but can move toward anticipatory care, reducing delays in recognition and intervention. In time-critical settings like trauma surgery or emergency laparotomies, this anticipatory capacity can be life-saving [15].

However, challenges persist. Concerns around algorithm transparency (“black box” models), clinical validation, and over-reliance on machine recommendations remain. Additionally, AI tools must be rigorously tested in diverse surgical populations to ensure equity and reliability. Importantly, these technologies should augment not replace the clinical judgment of experienced teams [16].

Still, the trajectory is clear: AI is reshaping perioperative care from intuition-based to data-informed decision-making, thereby enhancing safety, consistency, and outcomes [17].

Smart wearables: extending the surgical team’s eyes and ears

The integration of smart wearable devices in the perioperative setting is transforming the way surgical teams monitor and respond to patient status. These tools ranging from biometric wristbands and adhesive biosensors to smart garments allow for continuous real-time monitoring of vital signs, activity levels, and stress indicators [18].

Unlike traditional intermittent monitoring methods, wearables offer a stream of real-time data that can detect early signs of complications, such as hemodynamic instability, hypoxia, or infection. For instance, continuous oxygen saturation monitoring via a wearable pulse oximeter can alert staff to postoperative hypoxia sooner than periodic vital sign checks. Similarly, wearable ECG patches can detect arrhythmias or ischemic changes without requiring bulky bedside monitoring [19].

From a patient safety perspective, wearables act as an extension of the surgical team’s sensory and cognitive capacity. In busy postoperative units or during patient transfers, these devices serve as silent sentinels, maintaining a digital eye on parameters that would otherwise go unchecked. Moreover, their data can be integrated with electronic health records (EHRs) and clinical decision support systems (CDSS), enabling predictive analytics and early warning alerts [20, 21].

Despite their promise, challenges remain in terms of data overload, interoperability, cost, and concerns about patient comfort and data privacy. Additionally, surgical teams must be trained to interpret wearable-generated data within the specific context of perioperative physiology, where fluctuations may be expected or transient [22].

Nevertheless, smart wearables represent a powerful frontier in enhancing situational awareness and early intervention two pillars of perioperative patient safety. As technologies evolve and become more user-friendly and integrated, they are likely to become standard components of perioperative care protocols [23, 24].

Digital checklists and cognitive aids: standardizing safety behaviors

Checklists are among the most effective tools to reduce surgical errors and standardize safety practices. The WHO Surgical Safety Checklist demonstrated global impact by lowering perioperative mortality and complications through structured team communication and verification of critical steps. However, paper-based checklists often suffer from incomplete compliance and may be reduced to routine “tick-box” exercises [25].

The transition to digital checklists offers important advantages. These tools can adapt dynamically to procedure type, patient-specific risk factors, or intraoperative events. For example, digital prompts can highlight time-sensitive actions such as antibiotic administration or anticoagulation checks. When integrated with decision support systems, they also provide real-time alerts about omissions, enhancing accountability and protocol adherence [26].

Cognitive aids such as interactive flowcharts and voice-activated guidance further support crisis management during rare but high-risk events like malignant hyperthermia or massive hemorrhage. By reducing cognitive load and aligning team actions, they improve coordination in stressful scenarios [27].

Despite challenges such as resistance to change or concerns about technology fatigue, digital checklists and cognitive aids remain powerful, low-cost tools. When properly designed and embedded into workflows, they not only reduce preventable errors but also promote a culture of safety, particularly in teaching and high-volume surgical centers [28].

Surgical robotics: precision and safety through automation

The rise of surgical robotics marks a transformative milestone in modern operating rooms, offering enhanced precision, stability, and visualization far beyond human capability. Robotic-assisted procedures, particularly in urology, gynecology, and general surgery, are increasingly being adopted not only for their ergonomic and technical advantages but also for their potential impact on patient safety [29].

Robotic platforms such as the da Vinci Surgical System enable surgeons to perform minimally invasive procedures with tremor-free movements, three-dimensional magnified vision, and high degrees of articulation. These features reduce the likelihood of tissue damage, bleeding, and inadvertent injury to adjacent structures. As a result, robotic surgeries often yield shorter hospital stays, lower infection rates, and faster recovery times all key indicators of safer perioperative care [30].

Importantly, robotics also supports greater standardization and reproducibility in surgical technique. Unlike purely manual surgery, where performance may vary based on fatigue or skill level, robotic systems can minimize operator variability through motion scaling and haptic feedback. Some systems now include real-time safety features, such as proximity sensors or movement restriction protocols that prevent instruments from straying into sensitive anatomical zones [31].

Robotics also facilitates tele mentoring and remote surgery, potentially improving access to high-quality care in underserved regions. Through telepresence, expert surgeons can guide or even perform procedures across distances, reducing time to intervention in critical cases [32].

Recent studies also highlight the role of robotics in enhancing intraoperative data integration and AI-assisted decision-making. For instance, AI algorithms can provide real-time guidance for instrument positioning or predict high-risk events during robotic procedures, further reducing complications. Additionally, tele-mentoring and remote surgery capabilities are increasingly explored, potentially improving access to high-quality surgical care in underserved regions [33].

However, robotics is not without challenges. The learning curve for robotic proficiency can be steep, and inadequate training may compromise safety rather than enhance it. Additionally, system failures, delayed response in emergencies, and high cost remain barriers to widespread adoption. Furthermore, robotic systems must be evaluated not only on clinical outcomes but also on workflow integration and team dynamics [34].

In summary, when integrated into a well-trained and well-prepared surgical team, robotic technology enhances technical precision and creates new frontiers for safety provided its use is matched by robust training, governance, and patient-centered evaluation.

Digital twin technology: a new dimension in surgical risk modeling

The concept of digital twins virtual replicas of physical systems is rapidly gaining momentum in healthcare, especially in the context of predictive modeling and surgical planning. A digital twin in surgery involves creating a highly detailed computational model of an individual patient, integrating anatomical, physiological, and sometimes even behavioral data to simulate how that patient might respond to specific surgical interventions.

By using multimodal inputs like imaging (CT/MRI), biometric data, lab results, and medical history, a patient’s digital twin can be built preoperatively. Surgeons and anesthesiologists can then “test drive” a procedure virtually, analyzing different approaches and predicting potential complications in a low-risk environment. For example, in complex cardiovascular or neurosurgical procedures, a digital twin might help estimate blood loss, identify high-risk anatomical variations, or simulate hemodynamic responses [35, 36].

From a patient safety perspective, digital twins represent a paradigm shift. They allow for personalized risk stratification, helping clinicians identify the safest path forward for high-risk patients. In trauma or emergency surgery, rapidly generated digital twins may one day support real-time decisions when minutes count.

Moreover, these models can be continuously updated as patient data evolves. For instance, if a patient’s renal function deteriorates the night before surgery, the digital twin can recalculate drug dosing or fluid management scenarios. This dynamic modeling capability enhances safety and precision across the perioperative timeline [37].

Digital twins are also valuable in surgical training and system optimization. Trainees can rehearse procedures on simulated patient-specific cases, while hospitals can use aggregated digital twin data to refine protocols and predict resource needs. Yet, the technology is in its early stages. Barriers include computational demands, standardization of input data, ethical concerns over data privacy, and the risk of over-reliance on simulations that may not capture rare or emergent intraoperative events. Nonetheless, the promise is compelling: with digital twins, we are moving closer to a future in which no patient undergoes a procedure unmodeled where safety is not just reactive, but proactively engineered into every surgical plan [38].

Augmented reality and intraoperative visualization: enhancing surgical precision and team awareness

Augmented Reality (AR) is transforming the way surgeons visualize anatomy, pathology, and spatial relationships during procedures. By overlaying virtual information such as 3D models, real-time imaging, or anatomical landmarks onto the surgeon’s visual field, AR creates a powerful interface that enhances decision-making and minimizes intraoperative risk [39].

In complex surgeries such as hepatobiliary, orthopedic, or neurosurgical procedures, precise localization of critical structures like vessels, tumors, or nerves is essential to avoid unintended injury. AR systems, integrated with preoperative imaging and navigation tools, enable surgeons to “see beneath the surface” in real time. For instance, an AR headset or screen can project the exact position of a hepatic vein while dissecting liver parenchyma, reducing the likelihood of bleeding or bile duct damage [40].

Beyond individual surgeon benefit, AR can enhance team situational awareness. When displays are shared with scrub nurses, anesthesiologists, or assistants, the entire team gains a common spatial understanding of the procedure, improving coordination and communication two pillars of patient safety. Moreover, AR can integrate with robotic systems and surgical microscopes, allowing for gesture-based control or voice commands, reducing the need to touch surfaces and helping maintain sterility. Some platforms even allow remote experts to annotate the surgical field in real time, offering mentorship during critical moments [41].

Emerging studies also demonstrate that AR combined with intraoperative AI analytics can highlight areas of potential anatomical conflict or suggest optimized surgical pathways, supporting precision and safety. Moreover, AR is increasingly employed in surgical education and simulation, enabling trainees to rehearse procedures safely, receive performance feedback, and build expertise in a risk-free environment [42].

Despite its promise, AR faces challenges, including technology cost, hardware discomfort (e.g., prolonged use of headsets), and the risk of visual clutter or distraction if poorly designed. Additionally, integration with hospital IT systems and real-time imaging remains technically complex [43].

Still, the overarching benefit is clear: AR is not merely a visual aid it’s a safety-enhancing tool, expanding what surgeons can perceive, anticipate, and avoid [44].

Research gaps and future directions

Although smart technologies have significantly advanced perioperative safety, important research gaps remain. Further studies are needed to evaluate the long-term impact of these technologies on clinical outcomes and healthcare costs. Future research should also focus on developing international standards for assessing technology effectiveness and adaptability across diverse clinical settings.

Investigations into improving human-technology interaction, reducing cognitive load, and addressing ethical and privacy concerns are critical. Lastly, efforts to develop affordable and accessible technologies for resource-limited settings will be essential to promote equitable surgical safety worldwide.

Conclusion: toward a digitally enhanced culture of safety in surgery

As surgical care continues to evolve, digital technologies are emerging not as optional add-ons, but as essential components in building a proactive culture of safety. From AI-driven decision support and robotic assistance to digital twins and augmented reality, these innovations hold immense potential to reduce human error, enhance intraoperative precision, and foster better team communication all critical determinants of patient outcomes.

However, technology alone cannot ensure safety. Its successful integration depends on a robust foundation of training, interdisciplinary collaboration, ethical governance, and human-centered design. Healthcare teams must be equipped not only with tools, but with the competencies to use them wisely, and the willingness to question and refine their processes continuously.

Additionally, equity must be prioritized. Digital solutions should be designed and implemented in a way that narrows, rather than widens, the gap between resource-rich and resource-limited settings. Technologies that support remote mentoring, simulation-based training, or risk modeling for low-resource environments can democratize access to safer surgical care.

Ultimately, the digital transformation of surgery must be guided by a singular purpose: to protect patients. This requires a shift from reactive risk management to proactive, data-informed, team-based strategies that anticipate complications before they arise. As we move forward, collaboration between clinicians, engineers, data scientists, and policymakers will be essential to ensure that safety remains at the heart of every innovation.

The future of surgery should not only be smarter, but also safer from a patient-centric care perspective. By embracing digital tools as allies in this mission, we can build operating rooms where precision, empathy, and vigilance co-exist and where every patient receives care that is as safe as it is sophisticated.

Author contributions

The author was solely responsible for the conceptualization of the review topic, the design and refinement of the research question, literature search and selection, critical reading and synthesis of the included studies, and the writing and final approval of the manuscript.

Funding

This research received no external funding.

Data availability

Any materials reviewed for the content of this manuscript can be made available upon request.

Declarations

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Competing interests

The authors declare no competing interests.

Footnotes

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

  • 1.Stoumpos AI, Kitsios F, Talias MA. Digital transformation in healthcare: technology acceptance and its applications. Int J Environ Res Public Health. 2023;20(4):3407. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Endalamaw A, Zewdie A, Wolka E, Assefa Y. A scoping review of digital health technologies in Multimorbidity management: mechanisms, outcomes, challenges, and strategies. BMC Health Serv Res. 2025;25(1):382. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Baumgarten M, Brødsgaard A, Nørholm V, Foss NB, Bunkenborg G. Interprofessional collaboration between nurses and physicians in the perioperative period. J PeriAnesthesia Nurs. 2023;38(5):724–31. [DOI] [PubMed] [Google Scholar]
  • 4.World Health Organization. WHO guidelines for safe surgery 2009: safe surgery saves lives. Geneva, Switzerland: WHO; 2009. pp. 1–10. [PubMed] [Google Scholar]
  • 5.Michard F, Saugel B. New sensors for the early detection of clinical deterioration on general wards and beyond - a clinician’s perspective. J Clin Monit Comput. 2025;39(2):435–42. [DOI] [PubMed] [Google Scholar]
  • 6.Deol ES, et al. Artificial intelligence model for automated surgical instrument detection and counting: an experimental proof-of-concept study. Patient Saf Surg. 2024;18:24. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Amir AS, Mulyana D, Dida S, Suminar JR, editors. Enhancing Doctor-Patient Communication through Digital Media Platforms: A Study on Innovation in Health Interaction. Proceeding of The International Conference of Inovation, Science, Technology, Education, Children, and Health; 2024.
  • 8.Joshi M, Ashrafian H, Arora S, Sharabiani M, McAndrew K, Khan SN, et al. A pilot study to investigate real-time digital alerting from wearable sensors in surgical patients. Pilot Feasibility Stud. 2022;8(1):140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Kenig N, Monton Echeverria J, Muntaner Vives A. Artificial intelligence in surgery: A systematic review of use and validation. J Clin Med. 2024;13:23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Hashimoto DA, Rosman G, Rus D, Meireles OR. Artificial intelligence in surgery: promises and perils. Ann Surg. 2018;268(1):70–6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Ke YH et al. Real-world deployment and evaluation of PEri-operative AI chatbot (PEACH): a large Language model chatbot for peri-operative medicine. Anaesth 2025 Sep 19 (Online ahead of print). [DOI] [PubMed]
  • 12.Stam WT, Goedknegt LK, Ingwersen EW, Schoonmade LJ, Bruns ER, Daams F. The prediction of surgical complications using artificial intelligence in patients undergoing major abdominal surgery: a systematic review. Surgery. 2022;171(4):1014–21. [DOI] [PubMed] [Google Scholar]
  • 13.Arjmandnia F, et al. The value of machine learning technology and artificial intelligence to enhance patient safety in spine surgery: a review. Patient Saf Surg. 2024;18:11. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Khalifa M, Albadawy M, Iqbal U. Advancing clinical decision support: the role of artificial intelligence across six domains. Comput Methods Programs Biomed Update. 2024;5:100142. [Google Scholar]
  • 15.Colborn K, Brat G, Callcut R. Predictive analytics and artificial intelligence in Surgery-Opportunities and risks. JAMA Surg. 2023;158(4):337–8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Kelly CJ, Karthikesalingam A, Suleyman M, Corrado G, King D. Key challenges for delivering clinical impact with artificial intelligence. BMC Med. 2019;17:1–9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Akter MS, Sultana N, Khan MAR, Mohiuddin M. Business intelligence-driven healthcare: integrating big data and machine learning for strategic cost reduction and quality care delivery. Am J Interdisciplinary Stud. 2023;4(02):01–28.
  • 18.Cloß K, Verket M, Müller-Wieland D, et al. Application of wearables for remote monitoring of oncology patients: a scoping review. Digit HEALTH. 2024;10. [DOI] [PMC free article] [PubMed]
  • 19.Amin T, Mobbs RJ, Mostafa N, Sy LW, Choy WJ. Wearable devices for patient monitoring in the early postoperative period: a literature review. Mhealth. 2021;7:50. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Breteler MJ, KleinJan EJ, Dohmen DA, Leenen LP, van Hillegersberg R, Ruurda JP, et al. Vital signs monitoring with wearable sensors in high-risk surgical patients: a clinical validation study. Anesthesiology. 2020;132(3):424–39. [DOI] [PubMed] [Google Scholar]
  • 21.Breteler MJ, Huizinga E, van Loon K, Leenen LP, Dohmen DA, Kalkman CJ, et al. Reliability of wireless monitoring using a wearable patch sensor in high-risk surgical patients at a step-down unit in the netherlands: a clinical validation study. BMJ Open. 2018;8(2):e020162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Feng Z, Bhat RR, Yuan X, Freeman D, Baslanti T, Bihorac A, et al. editors. Intelligent perioperative system: towards real-time big data analytics in surgery risk assessment. 2017 IEEE 15th Intl Conf on Dependable, Autonomic and Secure Computing, 15th Intl Conf on Pervasive Intelligence and Computing, 3rd Intl Conf on Big Data Intelligence and Computing and Cyber Science and Technology Congress (DASC/PiCom/DataCom/CyberSciTech); 2017: IEEE. [DOI] [PMC free article] [PubMed]
  • 23.Hedrick TL, Hassinger TE, Myers E, Krebs ED, Chu D, Charles AN, et al. Wearable technology in the perioperative period: predicting risk of postoperative complications in patients undergoing elective colorectal surgery. Dis Colon Rectum. 2020;63(4):538–44. [DOI] [PubMed] [Google Scholar]
  • 24.Kolovos P. Wearable technologies in post-operative recovery: clinical applications and positive impacts. Int J Caring Sci. 2020;13(2):1474. [Google Scholar]
  • 25.Kulp L, Sarcevic A, Cheng M, Zheng Y, Burd RS, editors. Comparing the effects of paper and digital checklists on team performance in time-critical work. Proceedings of the 2019 CHI Conference on Human Factors in Computing Systems; 2019. [DOI] [PMC free article] [PubMed]
  • 26.Pati AB, Mishra TS, Chappity P, Venkateshan M, Pillai JS. Use of technology to improve the adherence to surgical safety checklists in the operating room. Joint Comm J Qual Patient Saf. 2023;49(10):572–6. [DOI] [PubMed] [Google Scholar]
  • 27.Greig P, Zolger D, Onwochei D, Thurley N, Higham H, Desai N. Cognitive aids in the management of clinical emergencies: a systematic review. Anaesthesia. 2023;78(3):343–55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 28.Daly Guris RJ, Lane-Fall MB. Checklists and cognitive aids: underutilized and under-researched tools to promote patient safety and optimize clinician performance. Curr Opin Anaesthesiol. 2022;35(6):723–7. [DOI] [PubMed] [Google Scholar]
  • 29.Hu Y, Strong VE. Robotic surgery and oncologic outcomes. JAMA Oncol. 2020;6(10):1537–9. [DOI] [PubMed] [Google Scholar]
  • 30.Douissard J, Hagen ME, Morel P. The da Vinci surgical system. Bariatric robotic surgery: a comprehensive guide. 2019:13–27.
  • 31.Wah JNK. Revolutionizing surgery: AI and robotics for precision, risk reduction, and innovation. J Robotic Surg. 2025;19(1):1–15. [DOI] [PubMed] [Google Scholar]
  • 32.Liu Z, Huang J, Zhang H, Zhang S, Dai H, Jiang Y, et al. The application of robotic and artificial intelligence technologies in spinal surgery: a review focused on prospects in remote areas of China. J Robot Surg. 2025;19(1):594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 33.SHAFIK W. Remote Surgery and Robotic-Assisted Procedures: Technologies, Benefits and Limitations, Applications, Regulatory Framework, and Future Trends. Revolutionary Impact of 5G on Advancement of Technology in Healthcare. 2025:23.
  • 34.Picozzi P, Nocco U, Puleo G, Labate C, Cimolin V. Telemedicine and robotic surgery: a narrative review to analyze advantages, limitations and future developments. Electronics. 2023;13(1):124. [Google Scholar]
  • 35.Corral-Acero J, Margara F, Marciniak M, Rodero C, Loncaric F, Feng Y, et al. The ‘Digital twin’to enable the vision of precision cardiology. Eur Heart J. 2020;41(48):4556–64. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 36.Li N, et al. Artificial intelligence and machine learning in transfusion practice: an analytical assessment. Transfus Med Rev. 2025;39(4):150926. [DOI] [PubMed] [Google Scholar]
  • 37.Erol T, Mendi AF, Doğan D, editors. The digital twin revolution in healthcare. 2020 4th international symposium on multidisciplinary studies and innovative technologies (ISMSIT); 2020: IEEE.
  • 38.Bruynseels K, Van den Santoni de Sio F. Digital twins in health care: ethical implications of an emerging engineering paradigm. Front Genet. 2018;9:31. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 39.Ghaednia H, Fourman MS, Lans A, Detels K, Dijkstra H, Lloyd S, et al. Augmented and virtual reality in spine surgery, current applications and future potentials. Spine J. 2021;21(10):1617–25. [DOI] [PubMed] [Google Scholar]
  • 40.Furman AA, Hsu WK. Augmented reality (AR) in orthopedics: current applications and future directions. Curr Rev Musculoskelet Med. 2021:1–9. [DOI] [PMC free article] [PubMed]
  • 41.Ayoub A, Pulijala Y. The application of virtual reality and augmented reality in oral & maxillofacial surgery. BMC Oral Health. 2019;19:1–8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 42.Suresh D, Aydin A, James S, Ahmed K, Dasgupta P. The role of augmented reality in surgical training: a systematic review. Surg Innov. 2023;30(3):366–82. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 43.Dargan S, Bansal S, Kumar M, Mittal A, Kumar K. Augmented reality: A comprehensive review. Arch Comput Methods Eng. 2023;30(2):1057–80. [Google Scholar]
  • 44.Munzer BW, Khan MM, Shipman B, Mahajan P. Augmented reality in emergency medicine: a scoping review. J Med Internet Res. 2019;21(4):e12368. [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

Any materials reviewed for the content of this manuscript can be made available upon request.


Articles from Patient Safety in Surgery are provided here courtesy of BMC

RESOURCES