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IL-1β and IL-2 expression from LN cells. IL-1β and IL-2 expression was increased in LN cell supernatants isolated from collagen-immunized E/P-selectin mutant mice compared with immunized wild-type mice. Pre-onset, post-onset, and chronic arthritis time points were combined. LN supernatants were stimulated with 5 μg/ml chick II collagen. Values are expressed as mean ± standard error of the mean. *P < 0.05. LN, lymph node; n, number of separate cultures; wt, wild-type.
