Table 1.
Type of neutropenia | Neutropenias |
Congenital | Severe infantile agranulocytosis (Kostmann's syndrome) |
Shwachman–Diamond–Oski syndrome | |
Myelokathexis/neutropenia with tetraploid nuclei | |
Cyclic neutropenia | |
Chediak–Higashi syndrome | |
Reticular dysgenesis | |
Dyskeratosis congenita | |
Acquired | Postinfectious neutropenia |
Drug-induced neutropenia | |
Complement activation (haemodialysis, leukapheresis, ARDS) | |
Immune neutropenia | |
Isoimmune neonatal neutropenia | |
Alloimmune neutropenia (transfusion reaction) | |
Autoimmune neutropenia – primary | |
Benign of childhood | |
Adult chronic form | |
Autoimmune neutropenia – secondary | |
Autoimmune diseases | |
Large granular lymphocyte | |
Other (see Table 3) | |
Pure white cell aplasia | |
Chronic idiopathic neutropenia | |
Hypersplenism | |
Nutritional deficiency (vitamin B12 or folate deficiency) | |
Diseases affecting the bone marrow | |
Postchemotherapy | |
Aplastic anaemia | |
Fanconi anaemia | |
Myelodysplastic syndrome | |
Acute and chronic leukaemia |
ARDS, acute respiratory distress syndrome.