Table 2.
Comparisons | Number of genes differentially expressed | |||
Tissue A (number of samples) | Tissue B (number of samples) | Total | Up | Down |
WntH (7) | VMG (5) | 584 | 121 | 463 |
WntT (23) | WntH (7) | 388* | 112 | 276 |
WntT (23) | NeuT (12) | 1,296 | 624 | 672 |
NeuT (12) | VMG (5) | 1,263* | 419 | 844 |
WntT, H-ras mutant (12) | WntT, H-ras wild-type (9) | 40 | 31 | 9 |
WntT/p53-/- | WntT (10) | 113 | 43 | 70 |
WntT/Pten+/- LOH (3) | WntT (10) | 115 | 45 | 70 |
Expression ratio is computed by dividing the average expression level of the A group by the average expression level of the B group. The numbers of differentially expressed genes were determined by random permutation (P < 0.001), as described in the Materials and method section. *In selected comparisons, to reduce potential false signals due to stromal effects, the genes that were less than three-fold different in expression were filtered out from the listed total number of genes. LOH, loss of heterozygosity.