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. 2025 Oct 17;13:1628506. doi: 10.3389/fped.2025.1628506

Figure 1.

Receiver Operating Characteristic (ROC) curves comparing sIgE/tIgE and sIgE across four groups. Panel (a) shows all samples with better performance for sIgE/tIgE. Panel (b) covers egg protein group, (c) milk sample group, and (d) wheat sample group, with varying AUC values indicating performance differences.

ROC curve assessing the relationship of the sIgE level and sIgE/tIgE ratio with oral food challenge results sIgE, allergen-specific IgE. (a) ROC for All sample group, sIgE/tIgE AUC 0.814, 95% CI: 0.756–0.871 (p < 0.05); sIgE AUC 0.730, 95% CI: 0.663–0.797 (p < 0.05). (b) ROC for egg protein group, slgE/tlgE AUC 0.730, 95% CI: 0.610–0.850 (p < 0.05); sIgE AUC 0.668, 95% CI: 0.539–0.797 (p < 0.05). (c) ROC for milk sample group, sIgE/tIgE AUC 0.890, 95% CI: 0.802–0.979 (p < 0.05); sIgE AUC 0.839, 95% CI: 0.732–0.945 (p < 0.05). (d) ROC for wheat sample group, sIgE/tIgE AUC 0.813, 95% CI: 0.691–0.935 (p < 0.05); sIgE AUC 0.810, 95% CI: 0.692–0.927 (p < 0.05).