Figure 6.
Food intake, energy expenditure, and activity studies. (A) Food intake measured over 14 days in LGsKO (black bars) and control (white bars) mice (n = 6/group). (B) Resting and total O2 consumption, (C) total and ambulatory (Amb) activity levels, and (D) resting and total RER measured over 24 hours at 22°C (left) and 30°C (right) (n = 6/group). Time course of total O2 consumption rate (E), total RER (F), and total activity(G) over a 45-hour period (fed, hours 1–21; fasting, hours 22–45) at 22°C in LGsKO (filled triangles) and control (filled squares) mice (n = 6/group). To the right of each graph are panels showing the mean ± SEM of each parameter during the fed and fasting periods.*P < 0.05; **P < 0.01. vO2, volume of O2 consumed.