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. 2025 Oct 30;16:9592. doi: 10.1038/s41467-025-64343-9

Table 2.

Table summarising all the ENCODE collections

Collection Description Total numbers* Link
ENCORE matrix The ENCORE matrix summarises assays performed to study protein-RNA interactions of RNA-binding proteins (RBPs) encoded in the human genome. 1832 http://tinyurl.com/encore-matrix
Immune cells matrix Immune cells matrix summarises epigenomic profiling of human immune cells at different cellular fates and states, including activation, stimulation, and disease (MS). 1736 http://tinyurl.com/Immune-matrix
Stem cells differentiation matrix Stem cells differentiation matrix summarises assays performed on 3 different stem cells (H1, H9, PGP) and their in vitro differentiated derivatives. 781 http://tinyurl.com/stem-cell-matrix
Deeply profiled cell lines matrix The deeply profiled cell lines matrix represents data from cell lines that have been extensively studied within the ENCODE project. 6474 http://tinyurl.com/deeply-profiled
Protein Knockdown/Degron matrix This matrix displays experiments that were performed on transformed HCT116 cell lines, utilising the auxin-inducible Degron (AID) system. 252 http://tinyurl.com/degron-matrix
Human donor matrix The Human Donor Matrix provides a matrix view of assays performed on biosamples derived from individual human donors. 6978 http://tinyurl.com/human-donor-matrix
ENTEx matrix The ENTEx matrix displays approximately 30 overlapping tissues from four individual donors, which were sampled in a collaborative effort with the GTEx Consortium. 1567 http://tinyurl.com/entex-matrix
Rush Alzheimer’s Disease Study Matrix Human brain samples collection page that includes data from multiple brain regions collected from individuals with various levels of cognitive impairment. 664 http://tinyurl.com/brain-matrix
Reference Epigenomes matrix Project data from human tissue, cell line, primary cell, and in vitro differentiated cell biosamples, organised as reference epigenomes following guidelines set out by IHEC. 4145 http://tinyurl.com/reference-epigenome-matrix
Mouse development matrix The mouse development matrix displays embryonic to postnatal mouse developmental time course data across several tissues, organised as reference epigenomes. 1934 http://tinyurl.com/mouse-development-matrix

*Note: Refer to Fig. 5 for a more comprehensive breakdown of the total number of datasets within each category.