Table 3.
Selected hematologic and organ weight parameters (mean ± SEM) for rats implanted with metal pellets for 1 month.
| Ta | WA (low) | WA (high) | |
|---|---|---|---|
| White blood cells (103/μL) | 3.86 ± 0.20 | 3.81 ± 0.14 | 3.86 ± 0.21 |
| Red blood cells (106/μL) | 7.84 ± 0.08 | 7.74 ± 0.07 | 8.50 ± 0.07** |
| Hemoglobin (g/dL) | 13.65 ± 0.15 | 14.81 ± 0.16 | 15.84 ± 0.14** |
| Hematocrit (%) | 40.15 ± 0.42 | 39.66 ± 0.50 | 43.29 ± 0.35** |
| MCV (fL) | 51.20 ± 0.14 | 51.22 ± 0.31 | 50.98 ± 0.19 |
| MCH (pg) | 17.41 ± 0.05 | 19.12 ± 0.09 | 18.64 ± 0.19** |
| MCHC (g/dL) | 34.01 ± 0.12 | 37.37 ± 0.29 | 36.56 ± 0.41** |
| RDW (%) | 12.21 ± 0.11 | 12.69 ± 0.11 | 14.18 ± 0.18** |
| Platelets (103/μL) | 646.50 ± 18.76 | 641.00 ± 17.97 | 756.20 ± 43.48* |
| MPV (fL) | 7.91 ± 0.40 | 8.56 ± 0.39 | 9.90 ± 0.55* |
| Neutrophils (103/μL) | 0.65 ± 0.04 | 0.79 ± 0.05 | 0.81 ± 0.04** |
| Lymphocytes (103/μL) | 3.04 ± 0.18 | 2.85 ± 0.13 | 2.90 ± 0.18 |
| Monocytes (103/μL) | 0.06 ± 0.00 | 0.06 ± 0.01 | 0.07 ± 0.00 |
| Eosinophils (103/μL) | 0.07 ± 0.01 | 0.08 ± 0.01 | 0.05 ± 0.00* |
| Basophils (103/μL) | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.01 ± 0.00 |
| Spleen (mg/g bw) | 2.37 ± 0.06 | 2.42 ± 0.05 | 2.73 ± 0.04** |
| Thymus (mg/g bw) | 1.07 ± 0.03 | 1.14 ± 0.04 | 1.06 ± 0.03 |
| Liver ((mg/g bw) | 34.47 ± 0.26 | 34.31 ± 0.22 | 34.18 ± 0.61 |
| Kidney (mg/g bw) | 6.17 ± 0.08 | 6.06 ± 0.06 | 5.91 ± 0.05* |
| Testes (mg/g bw) | 10.10 ± 0.16 | 9.86 ± 0.13 | 9.98 ± 0.11 |
Abbreviations: bw, body weight; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MPV, mean platelet volume; RDW, red blood cell distribution width. Data represent mean ± SEM of 15 observations.
*
p < 0.05, and
**
p < 0.01 compared with the age-matched Ta control group by one-way ANOVA followed by Dunnett’s test for group mean comparisons.