Table 3.
Twelve different types of Cys-PTM, metal binding modifications present in this database.
| Cysteine PTM metal modifications | Number of entries | Proteins involved (number of entries in this database) |
|---|---|---|
| Fe(II) | 217 | Peroxidase (96), Cytochrome (ETC transmembrane protein) (49), Myoglobin (39), Catalase (23) |
| Zn(II) | 192 | Super oxide dismuatase (SOD) (39) |
| Ca(II) | 113 | Protein kinase (14), Hedgehog (13) |
| Mo(II) | 98 | Protein-methionine-sulfoxide reductase (Msr) (81), Aldehyde oxidase (10), Xanthine oxidase (7) |
| Mg(II) | 57 | ATP synthetase (21) |
| 2Fe–2S | 25 | CDGSH iron–sulphur domain-containing protein (3), NADH-quinone oxidoreductase (2), Succinate dehydrogenase iron–sulphur subunit (2), Xanthine oxidase (7), Aldehyde oxidase (9) |
| Mn(II) | 18 | Super oxide dismutase (SOD) (6), Arginase (3) |
| K(I) | 13 | Ascorbate peroxidase (12) |
| 4Fe–4S | 5 | NADH-quinone oxidoreductase (2), Succinate dehydrogenase iron–sulphur subunit (2) |
| Na(I) | 3 | P2X purinoceptor 7 (P2 × 7) (ATP receptor) (P2Z receptor) (Purinergic receptor) (3) |
| Ni(II) | 3 | Urease (3) |
| Cu(I) | 1 | Copper transfer ATPase (1)—ATP-driven copper [Cu(+)] ion pump |